ArticleAmerican journal of human genetics2015
The genetic ancestry of African Americans, Latinos, and European Americans across the United States.
Article in American journal of human genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 391 papers, 10 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
391 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Genetic ancestry and risk of atrial fibrillation in individuals of Black ethnicity in the UK Biobank.Open heart · 2026Pooled it
- Pooled it
- Ancestry-independent risk of venous thromboembolism in individuals with sickle cell trait vs factor V Leiden.Blood advances · 2024Pooled it
- HER2-low prevalence among Hispanic/Latino women with breast cancer: A systematic review and meta-analysis.PloS one · 2024Pooled it
- Pooled it
- Demographic reporting across a decade of neuroimaging: a systematic review.Brain imaging and behavior · 2022Pooled it
- Interventions to increase racial and ethnic minority accrual into cancer clinical trials: A systematic review.Cancer · 2022Pooled it
- Role of Polygenic Risk Score in Cancer Precision Medicine of Non-European Populations: A Systematic Review.Current oncology (Toronto, Ont.) · 2022Pooled it
- Is Our Science Representative? A Systematic Review of Racial and Ethnic Diversity in Orthopaedic Clinical Trials from 2000 to 2020.Clinical orthopaedics and related research · 2022Pooled it
- Progression on active surveillance for prostate cancer in Black men: a systematic review and meta-analysis.Prostate cancer and prostatic diseases · 2022Pooled it
- Genetic European Ancestry and Incident Diabetes in Black Individuals: Insights From the SPRINT Trial.Circulation. Genomic and precision medicine · 2022Trial
- Lipoprotein(a)-dependent cardiovascular risk in different populations: are thresholds the same?Annals of medicine · 2026Review
- Applicability of handheld laser scanning for nonmetric skeletal assessment in biological profile estimation: a preliminary two-case study.International journal of legal medicine · 2026Article
- Islet Autoantibody Patterns Vary by Race and Ethnicity and Area Deprivation Index for Individuals at Risk for Type 1 Diabetes.Diabetes care · 2026Article
- The Landscape of Genomic and Socioeconomic Variables in Patients with Colorectal Cancer Based on Genetic Ancestry.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026Article
- Forensic validation and population genetic evaluation of an MPS-based integrated microhaplotype and Y-SNP/STR (MY) system.Biochemistry and biophysics reports · 2026Article
- Assessing Hardy-Weinberg equilibrium in T2T-aligned 1000 genomes project.PLoS genetics · 2026Article
- Genome-wide association study and predictors of neonatal blood cell traits in Hispanic newborns.American journal of human genetics · 2026Article
- The Invisible Patient: Racism, Risk-Avoidance, and Structural Inequities in Modern Healthcare.Journal of racial and ethnic health disparities · 2026Review
- The genetic legacy of the 17th-century colonial capital of St. Mary's City.Current biology : CB · 2026Article
331 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
Over the past 500 years, North America has been the site of ongoing mixing of Native Americans, European settlers, and Africans (brought largely by the trans-Atlantic slave trade), shaping the early history of what became the United States. We studied the genetic ancestry of 5,269 self-described African Americans, 8,663 Latinos, and 148,789 European Americans who are 23andMe customers and show that the legacy of these historical interactions is visible in the genetic ancestry of present-day Americans. We document pervasive mixed ancestry and asymmetrical male and female ancestry contributions in all groups studied. We show that regional ancestry differences reflect historical events, such as early Spanish colonization, waves of immigration from many regions of Europe, and forced relocation of Native Americans within the US. This study sheds light on the fine-scale differences in ancestry within and across the United States and informs our understanding of the relationship between racial and ethnic identities and genetic ancestry.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.