Evidence map›Paper›PMID 25529366›Full record

ArticleThe Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases

Risk of vancomycin-resistant enterococci bloodstream infection among patients colonized with vancomycin-resistant enterococci.

Ahu Kara, İlker Devrim, Nuri Bayram, Nagehan Katipoğlu, Ezgi Kıran, Yeliz Oruç, Nevbahar Demiray, Hurşit Apa, Gamze Gülfidan

Abstract read
In one paragraph

Article in The Brazilian journal of infectious diseases : an official publication of the Brazilian Society of Infectious Diseases. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

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  13. Germs · 2017
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  16. Variation of Circulating Inflammatory Mediators in Staphylococcus aureus and Escherichia coli Bloodstream Infection.Medical science monitor : international medical journal of experimental and clinical research · 2016
    Article
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ahu KaraDepartment of Pediatric Infectious Disease, Dr. Behçet Uz Children's Hospital, İzmir, Turkey. Electronic address: ahukara01@hotmail.com.
İlker DevrimDepartment of Pediatric Infectious Disease, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.
Nuri BayramDepartment of Pediatric Infectious Disease, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.
Nagehan KatipoğluDepartment of Pediatrics, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.
Ezgi KıranDepartment of Pediatrics, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.
Yeliz OruçHospital Infection Control Committee, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.
Nevbahar DemirayHospital Infection Control Committee, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.
Hurşit ApaDepartment of Pediatrics, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.
Gamze GülfidanDepartment of Clinical Microbiology, Dr. Behçet Uz Children's Hospital, İzmir, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundVancomycin-resistant enterococci colonization has been reported to increase the risk of developing infections, including bloodstream infections.

aimIn this study, we aimed to share our experience with the vancomycin-resistant enterococci bloodstream infections following gastrointestinal vancomycin-resistant enterococci colonization in pediatric population during a period of 18 months.

methodA retrospective cohort of children admitted to a 400-bed tertiary teaching hospital in Izmir, Turkey whose vancomycin-resistant enterococci colonization was newly detected during routine surveillances for gastrointestinal vancomycin-resistant enterococci colonization during the period of January 2009 and December 2012 were included in this study. All vancomycin-resistant enterococci isolates found within 18 months after initial detection were evaluated for evidence of infection.

findingsTwo hundred and sixteen patients with vancomycin-resistant enterococci were included in the study. Vancomycin-resistant enterococci colonization was detected in 136 patients (62.3%) while they were hospitalized at intensive care units; while the remaining majority (33.0%) were hospitalized at hematology-oncology department. Vancomycin-resistant enterococci bacteremia was present only in three (1.55%) patients. All these patients were immunosuppressed due to human immunodeficiency virus (one patient) and intensive chemotherapy (two patients).

conclusionIn conclusion, our study found that 1.55% of vancomycin-resistant enterococci-colonized children had developed vancomycin-resistant enterococci bloodstream infection among the pediatric intensive care unit and hematology/oncology patients; according to our findings, we suggest that immunosupression is the key point for developing vancomycin-resistant enterococci bloodstream infections.

Indexed as

Vancomycin-Resistant EnterococciAdolescentBacteremiaChildChild, PreschoolCohort StudiesCross InfectionFemaleGram-Positive Bacterial InfectionsHumansImmunocompromised HostInfantInfant, NewbornIntensive Care Units, PediatricMaleRetrospective StudiesBloodstream infectionsColonizationImmunosupressionVancomycin-resistant enterococcus

Identifiers

PMID25529366
PMCPMC9425232

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.