ArticleEuropean journal of epidemiology2014
The Generation R Study: Biobank update 2015.
Article in European journal of epidemiology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 132 papers, 10 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
132 citing papers in PubMed, 10 syntheses or guidelines pooled it.
- Childhood internalising symptoms at ages 3 and 6: a meta-analysis of epigenome-wide associations from cord and peripheral blood.Journal of child psychology and psychiatry, and allied disciplines · 2026Pooled it
- Maternal caffeine consumption during pregnancy and offspring cord blood DNA methylation: an epigenome-wide association study meta-analysis.Epigenomics · 2023Pooled it
- DNA methylation signatures of aggression and closely related constructs: A meta-analysis of epigenome-wide studies across the lifespan.Molecular psychiatry · 2021Pooled it
- Epigenome-wide meta-analysis of blood DNA methylation in newborns and children identifies numerous loci related to gestational age.Genome medicine · 2020Pooled it
- Hypertensive Disorders of Pregnancy and DNA Methylation in Newborns.Hypertension (Dallas, Tex. : 1979) · 2019Pooled it
- Effect modification of FADS2 polymorphisms on the association between breastfeeding and intelligence: results from a collaborative meta-analysis.International journal of epidemiology · 2019Pooled it
- Maternal alcohol consumption and offspring DNA methylation: findings from six general population-based birth cohorts.Epigenomics · 2018Pooled it
- Fetal sex-specific differences in gestational age at delivery in pre-eclampsia: a meta-analysis.International journal of epidemiology · 2017Pooled it
- Maternal plasma folate impacts differential DNA methylation in an epigenome-wide meta-analysis of newborns.Nature communications · 2016Pooled it
- An epigenome-wide association meta-analysis of prenatal maternal stress in neonates: A model approach for replication.Epigenetics · 2016Pooled it
- Maternal and neonatal 25-hydroxyvitamin D concentrations and school-age lung function, asthma and allergy. The Generation R Study.Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology · 2019Trial
- Associations of Exposure to Common Plasticizers and Organophosphate Pesticides during Pregnancy and in Childhood with Cognitive Performance in Adolescents: A Population-Based Study.Environmental science & technology · 2026Article
- Prenatal and childhood exposure to common plasticizers in relation to emotional and behavioral development through adolescence.The Science of the total environment · 2026Article
- Maternal Early-Pregnancy Cardiovascular Health and Offspring Emotional, Behavioral, and Cognitive Outcomes in Adolescence.Journal of the American Heart Association · 2026Article
- Placental Growth Factor and Female Long-Term Hypertension.Journal of clinical medicine · 2025Article
- Predicting obesity at adolescence from an early age in a Dutch observational cohort study: the development and internal validation of a multivariable prediction model.BMC pediatrics · 2025Observational
- A genome-wide scan of non-coding RNAs and enhancers for refractive error and myopia.Human genetics · 2025Article
- Inflammatory markers in pregnancy - identifying drivers in four large cohorts.Frontiers in immunology · 2025Article
- Gender issues in myopia: a changing paradigm in generations.European journal of epidemiology · 2024Article
- Gestational organophosphate pesticide exposure and childhood cardiovascular outcomes.Environment international · 2024Article
72 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
18 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Generation R Study is a population-based prospective cohort study from fetal life until adulthood. The study is designed to identify early environmental and genetic causes and causal pathways leading to normal and abnormal growth, development and health from fetal life, childhood and young adulthood. In total, 9,778 mothers were enrolled in the study. Data collection in children and their parents include questionnaires, interviews, detailed physical and ultrasound examinations, behavioural observations, Magnetic Resonance Imaging and biological samples. Efforts have been conducted for collecting biological samples including blood, hair, faeces, nasal swabs, saliva and urine samples and generating genomics data on DNA, RNA and microbiome. In this paper, we give an update of the collection, processing and storage of these biological samples and available measures. Together with detailed phenotype measurements, these biological samples provide a unique resource for epidemiological studies focused on environmental exposures, genetic and genomic determinants and their interactions in relation to growth, health and development from fetal life onwards.
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Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.