Evidence map›Paper›PMID 25526452›Full record

ArticleMedicine2014

Behçet's disease complicated with thrombosis: a report of 93 Chinese cases.

Xiuhua Wu, Guohua Li, Xinxiang Huang, Li Wang, Wanli Liu, Yan Zhao, Wenjie Zheng

Open access · goldAbstract readMulticenter Study
In one paragraph

Article in Medicine, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
2.6field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 55 citations in OpenAlex.

  1. Renal Vein Thrombosis: A Narrative Review.Diagnostics (Basel, Switzerland) · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Venous Thromboembolism in Unusual Locations.The Medical clinics of North America · 2025
    Review
  7. Article
  8. Review
  9. Autoinflammatory diseases and the kidney.Immunologic research · 2023
    Review
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Vasculitis damage index in Behçet's disease.Advances in rheumatology (London, England) · 2021
    Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Xiuhua WuFrom the Department of Rheumatology and Clinical Immunology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Key Laboratory of Rheumatology and Clinical Immunology, Ministry of Education, Beijing, 100730, China (XW, LW, YZ, WZ); Department of Nephrology, Inner Mongolia Hospital of Traditional Chinese Medicine, Hohhot, 010020, China (GL); Department of Rheumatology and Hematology, the People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China, 530021 (XH); and MOE Key Laboratory of Protein Science, School of Life Sciences, Tsinghua University, Beijing, 100084, China (WL).
Guohua Li
Xinxiang Huang
Li Wang
Wanli Liu
Yan Zhao
Wenjie Zheng
Chinese Academy of Medical Sciences & Peking Union Medical College · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To investigate the clinical features of Behçet's disease (BD) complicated with thrombosis. Medical records of patients with BD at Peking Union Medical College Hospital from 1993 to 2013 were reviewed to identify thrombosis. Of the 766 patients with BD, 93 patients (16 female and 77 male) developed thrombosis. The most common thrombosis was extremity vein thrombosis (86.0%), including deep vein thrombosis (n=78) and superficial thrombophlebitis (n=4). The other thrombosis types associated with BD in descending frequency of order were: vena cava thrombosis (30.1%), pulmonary thromboembolism (15.1%), cerebral venous thrombosis (CVT) (12.9%), intracardiac thrombosis (8.6%), Budd-Chiari syndrome (7.5%), and renal vein thrombosis (4.3%), etc. Venous thrombosis is more frequent than arterial thrombosis, and most of patients (94.6%) experienced multiple thrombosis. A male predominance of extremity vein thrombosis and positive pathergy test, and a female predominance of CVT and genital ulcers were noted. All of these patients exhibited active disease during the emergence of thrombotic events. After treating with glucocorticosteroids, immunosuppressants, and/or anticoagulants, the thrombosis resolved in 89 patients. Three patients died from aneurysm rupture, myocardial infarction and Budd-Chiari syndrome, respectively. One patient with septic shock discontinued therapy during follow-up. Thrombosis in BD patients is male predominance, mainly multiple and venous thrombosis is more common. Active disease patients are prone to thrombosis, which suggest the key role of immunosuppressive therapy for the complication.

Indexed as

AdolescentAdultAgedBehcet SyndromeChinaFemaleFollow-Up StudiesHumansImmunosuppressive AgentsIncidenceMagnetic Resonance AngiographyMaleMiddle AgedPhlebographyRetrospective StudiesRisk AssessmentImmunosuppressive Agents

Identifiers

PMID25526452
PMCPMC4603137
OpenAlexW2318818663

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.