Evidence map›Paper›PMID 25526304›Full record

ReviewImmunity2014

Tissue-resident memory T cells.

Jason M Schenkel, David Masopust

Abstract readReview
In one paragraph

Review in Immunity, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 711 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
711citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

711 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Mucosal immunity and vaccine development.Signal transduction and targeted therapy · 2026
    Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. T Cell Thoughts.Immunological reviews · 2026
    Review
  10. Antigen-experienced airway CD8Science advances · 2026
    Article
  11. CD8Cell reports. Medicine · 2026
    Review
  12. Lung Resident T Cells Across the Spectrum of TB Infection and Disease.bioRxiv : the preprint server for biology · 2026
    Article
  13. Review
  14. CD8MedComm · 2026
    Review
  15. Review
  16. Article
  17. Immune responses in aging adults.The Journal of clinical investigation · 2026
    Review
  18. Article
  19. Article
  20. Article

651 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Jason M SchenkelDepartment of Microbiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA; Center for Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA.
David MasopustDepartment of Microbiology, University of Minnesota Medical School, Minneapolis, MN 55455, USA; Center for Immunology, University of Minnesota Medical School, Minneapolis, MN 55455, USA. Electronic address: masopust@umn.edu.

Funding

Mucosal T Cell Memory to PathogensR01AI084913 · NIAID · UNIVERSITY OF MINNESOTA · PI MASOPUST, DAVID · 2010 to 2023
$5.8M
IMMUNOLOGY TRAINING PROGRAMT32AI007313 · NIAID · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Carla Rothlin · 1989 to 2026
$5.7M
Regulation of T cell immunity within the female reproductive tractR01AI111671 · NIAID · UNIVERSITY OF MINNESOTA · PI MASOPUST, DAVID · 2014 to 2018
$2.4M
Mucosal T cell memory to pathogensR37AI084913 · NIAID · UNIVERSITY OF MINNESOTA · PI DAVID MASOPUST · 2024 to 2026
$1.7M
Trafficking & role of effector memory CD8T cell subsets in small intestineF30DK100159 · NIDDK · UNIVERSITY OF MINNESOTA · PI SCHENKEL, JASON M. · 2013 to 2015
$100k
NIAID NIH HHS R01 AI084913NIAID NIH HHS R01AI084913NIAID NIH HHS R01 AI111671NIAID NIH HHS R01AI111671NIAID NIH HHS R37 AI084913NIAID NIH HHS T32 AI007313NIDDK NIH HHS F30 DK100159
6 · The paper itself

Abstract

Tissue-resident memory T (Trm) cells constitute a recently identified lymphocyte lineage that occupies tissues without recirculating. They provide a first response against infections reencountered at body surfaces, where they accelerate pathogen clearance. Because Trm cells are not present within peripheral blood, they have not yet been well characterized, but are transcriptionally, phenotypically, and functionally distinct from recirculating central and effector memory T cells. In this review, we will summarize current knowledge of Trm cell ontogeny, regulation, maintenance, and function and will highlight technical considerations for studying this population.

Indexed as

Immunologic MemoryAnimalsCell DifferentiationCell MovementHumansImmunityT-LymphocytesT-Lymphocyte Subsets

Identifiers

PMID25526304
PMCPMC4276131

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.