ReviewLife (Basel, Switzerland)2014
Droplets: unconventional protocell model with life-like dynamics and room to grow.
Review in Life (Basel, Switzerland), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed.
- Behaviour and the Origin of Organisms.Origins of life and evolution of the biosphere : the journal of the International Society for the Study of the Origin of Life · 2023Article
- Survival strategies of artificial active agents.Scientific reports · 2023Article
- Self-preserving mechanisms in motile oil droplets: a computational model of abiological self-preservation.Royal Society open science · 2021Article
- Proliferating coacervate droplets as the missing link between chemistry and biology in the origins of life.Nature communications · 2021Article
- The Grayness of the Origin of Life.Life (Basel, Switzerland) · 2021Article
- Connecting primitive phase separation to biotechnology, synthetic biology, and engineering.Journal of biosciences · 2021Review
- Partitioning of amino acids and proteins into decanol using phase transfer agents towards understanding life in non-polar liquids.Scientific reports · 2019Article
- Nanoparticles Actively Fragment Armored Droplets.ACS nano · 2019Article
- Toward Experimental Evolution with Giant Vesicles.Life (Basel, Switzerland) · 2018Review
- Transport of Live Cells Under Sterile Conditions Using a Chemotactic Droplet.Scientific reports · 2018Article
- How a life-like system emerges from a simple particle motion law.Scientific reports · 2016Article
- Deformable Self-Propelled Micro-Object Comprising Underwater Oil Droplets.Scientific reports · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Over the past few decades, several protocell models have been developed that mimic certain essential characteristics of living cells. These protocells tend to be highly reductionist simplifications of living cells with prominent bilayer membrane boundaries, encapsulated metabolisms and/or encapsulated biologically-derived polymers as potential sources of information coding. In parallel with this conventional work, a novel protocell model based on droplets is also being developed. Such water-in-oil and oil-in-water droplet systems can possess chemical and biochemical transformations and biomolecule production, self-movement, self-division, individuality, group dynamics, and perhaps the fundamentals of intelligent systems and evolution. Given the diverse functionality possible with droplets as mimics of living cells, this system has the potential to be the first true embodiment of artificial life that is an orthologous departure from the one familiar type of biological life. This paper will synthesize the recent activity to develop droplets as protocell models.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.