ArticleEplasty2014
A systematic review of infection rates and associated antibiotic duration in acellular dermal matrix breast reconstruction.
Article in Eplasty, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The trial behind it
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Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 53 citations in OpenAlex.
- Consensus Review of Optimal Perioperative Care in Breast Reconstruction: Enhanced Recovery after Surgery (ERAS) Society Recommendations.Plastic and reconstructive surgery · 2017Guideline
- Antibiotics and Surgical Site Infection in Expander-Based Breast Reconstruction Trial (ASSERT).Annals of surgical oncology · 2026Trial
- Complications associated with acellular dermal matrix use in implant-based breast reconstruction.Gland surgery · 2026Review
- Different Surgical Approaches to the Treatment of Cleft Palate Fistulae as Perceived by Cleft Surgeons.The Cleft palate-craniofacial journal : official publication of the American Cleft Palate-Craniofacial Association · 2025Article
- Article
- Early Complications in Prepectoral Breast Reconstructions with and without Acellular Dermal Matrix: A Preliminary Analysis of Outcomes.Plastic and reconstructive surgery · 2024Article
- Evaluation of Xenograft Efficacy in Immediate Prosthesis-based Breast Reconstruction.Plastic and reconstructive surgery. Global open · 2022Article
- Preventing Infection in Implant-based Breast Reconstruction: Evaluating the Evidence for Common Practices and Standardized Protocols.Plastic and reconstructive surgery. Global open · 2022Article
- Tissue Expansion after Non-Skin-Sparing Mastectomy: A Comparative Study of Expansion Courses of Prepectoral and Subpectoral Tissue Expander Placement with Acellular Dermal Matrix.Journal of clinical medicine · 2021Article
- Prophylactic antibiotic use in acellular dermal matrix-assisted implant-based breast reconstruction.Annals of the Royal College of Surgeons of England · 2021Article
- Protocol for Prevention and Monitoring of Surgical Site Infections in Implant-Based Breast Reconstruction: Preliminary Results.Medicina (Kaunas, Lithuania) · 2021Article
- Breast reconstruction during the COVID-19 pandemic in resource-limited settings.GMS Interdisciplinary plastic and reconstructive surgery DGPW · 2021Review
- Comparison of irradiated and non-irradiated acellular dermal matrices in breast reconstruction under radiotherapy.Archives of plastic surgery · 2021Article
- Acellular Dermal Matrix Sterility: Does It Affect Microbial and Clinical Outcomes Following Implantation?Plastic and reconstructive surgery. Global open · 2019Article
- [Analysis of risk factors related to periprosthetic infection after breast augmentation].Zhongguo xiu fu chong jian wai ke za zhi = Zhongguo xiufu chongjian waike zazhi = Chinese journal of reparative and reconstructive surgery · 2019Article
- AlloDerm RTU Integration and Clinical Outcomes When Used for Reconstructive Breast Surgery.Plastic and reconstructive surgery. Global open · 2018Article
- One-Stage Immediate Breast Reconstruction: A Concise Review.BioMed research international · 2017Review
- Alloplastic adjuncts in breast reconstruction.Gland surgery · 2016Review
- Clinical applications of acellular dermal matrices: A review.Scars, burns & healingReview
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionReported infection rates in breast reconstruction with acellular dermal matrix (ADM) can exceed 31%. Prophylactic antibiotics remain controversial due to the absence of evidence-based literature. The purpose of this study was to examine published antibiotic regimens and their associated infection rates in this population.
methodsSystematic electronic searches were performed in PubMed, OVID, and the Cochrane databases for studies that reported on prophylactic antibiotic use and infection in patients undergoing ADM breast reconstruction. Two independent authors reviewed studies between 1970 and 2012 for inclusion and data extraction.
resultsA total of 863 studies were identified and abstracts reviewed. A total of 24 articles were included, with 2148 patients and 3189 ADM reconstructions. Mean infection rates varied between 0% and 31.25%, with a combined average of 11.59%. When comparing antibiotic protocols of less than 24 hours and more than 24 hours, the average infection rate was 2.48% and 13.21%, respectively.
conclusionThe current literature lacks consensus on the necessary duration for postoperative antibiotic prophylaxis following breast reconstruction. The potential increased risk of infection associated with ADM remains controversial. Because of the lack of supportive evidence, we do not recommend prolonged postoperative antibiotics in ADM breast reconstruction. LEVEL OF EVIDENCE: Therapeutic level III evidence.
Indexed as
Identifiers
25525481PMC4233926W312848856What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.