Evidence map›Paper›PMID 25525120›Full record

ReviewBritish medical bulletin2015

Yaws.

Michael Marks, Oriol Mitjà, Anthony W Solomon, Kingsley B Asiedu, David C Mabey

Open access · hybridAbstract readReview
In one paragraph

Review in British medical bulletin, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 46 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Yaws in Africa: Past, Present and Future.Diseases (Basel, Switzerland) · 2025
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. A Loop-Mediated Isothermal Amplification Assay for the Detection ofThe American journal of tropical medicine and hygiene · 2020
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 4 countries.

Michael MarksClinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK Hospital for Tropical Diseases, University College London Hospitals NHS Trust, Mortimer Market, London WC1E 6JB, UK michael.marks@lshtm.ac.uk.
Oriol MitjàBarcelona Centre for International Health Research, Hospital Clinic, University of Barcelona, Roselló 132, Barcelona, Spain Lihir Medical Centre-International SOS, Newcrest Mining, Lihir Island, Papua New Guinea.
Anthony W SolomonClinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK Hospital for Tropical Diseases, University College London Hospitals NHS Trust, Mortimer Market, London WC1E 6JB, UK Department of Control of Neglected Tropical Diseases, World Health Organization, Avenue Appia 20, 1211 Geneva 27, Switzerland.
Kingsley B AsieduDepartment of Control of Neglected Tropical Diseases, World Health Organization, Avenue Appia 20, 1211 Geneva 27, Switzerland.
David C MabeyClinical Research Department, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK Hospital for Tropical Diseases, University College London Hospitals NHS Trust, Mortimer Market, London WC1E 6JB, UK.
University of London · GBInstituto Oncológico Dr. Rosell · ESWorld Health Organization · CH

Funding

Wellcome Trust 100714Wellcome Trust 102807World Health Organization 001
6 · The paper itself

Abstract

introductionYaws, caused by Treponema pallidum ssp. pertenue, is endemic in parts of West Africa, Southeast Asia and the Pacific. The WHO has launched a campaign based on mass treatment with azithromycin, to eradicate yaws by 2020. SOURCES OF DATA: We reviewed published data, surveillance data and data presented at yaws eradication meetings. AREAS OF AGREEMENT: Azithromycin is now the preferred agent for treating yaws. Point-of-care tests have demonstrated their value in yaws. AREAS OF CONTROVERSY: There is limited data from 76 countries, which previously reported yaws. Different doses of azithromycin are used in community mass treatment for yaws and trachoma. GROWING POINTS: Yaws eradication appears an achievable goal. The programme will require considerable support from partners across health and development sectors. AREAS TIMELY FOR DEVELOPING RESEARCH: Studies to complete baseline mapping, integrate diagnostic tests into surveillance and assess the impact of community mass treatment with azithromycin are ongoing.

Indexed as

Disease EradicationYawsAnti-Bacterial AgentsAzithromycinCost-Benefit AnalysisHumansProgram DevelopmentSentinel SurveillanceTreponema pallidumAnti-Bacterial AgentsAzithromycineradicationneglected tropical diseasessyphilisyaws

Identifiers

PMID25525120
PMCPMC4350436
OpenAlexW4237839440

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.