Evidence map›Paper›PMID 25524548›Full record

ReviewCold Spring Harbor perspectives in biology2014

Sex chromosome drive.

Quentin Helleu, Pierre R Gérard, Catherine Montchamp-Moreau

Open access · bronzeAbstract readReview
In one paragraph

Review in Cold Spring Harbor perspectives in biology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 77 citations in OpenAlex.

  1. Article
  2. A Vertebrate Toxin-Antidote System That Sabotages Mouse Embryogenesis.bioRxiv : the preprint server for biology · 2026
    Article
  3. Signatures of sex ratio distortion in humans.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. A selfish supergene causes meiotic drive through both sexes inProceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Review
  8. Article
  9. Review
  10. An egg sabotaging mechanism drives non-Mendelian transmission in mice.bioRxiv : the preprint server for biology · 2024
    Article
  11. Article
  12. Article
  13. Review
  14. Mechanisms of meiotic drive in symmetric and asymmetric meiosis.Cellular and molecular life sciences : CMLS · 2021
    Review
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Quentin HelleuLaboratoire Évolution Génomes et Spéciation, CNRS UPR9034, Gif-sur-Yvette, France and Université Paris-Sud, Orsay, France.
Pierre R GérardLaboratoire Évolution Génomes et Spéciation, CNRS UPR9034, Gif-sur-Yvette, France and Université Paris-Sud, Orsay, France.
Catherine Montchamp-MoreauLaboratoire Évolution Génomes et Spéciation, CNRS UPR9034, Gif-sur-Yvette, France and Université Paris-Sud, Orsay, France.
Université Paris-Sud · FRGénétique Quantitative et Évolution Le Moulon · FR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sex chromosome drivers are selfish elements that subvert Mendel's first law of segregation and therefore are overrepresented among the products of meiosis. The sex-biased progeny produced then fuels an extended genetic conflict between the driver and the rest of the genome. Many examples of sex chromosome drive are known, but the occurrence of this phenomenon is probably largely underestimated because of the difficulty to detect it. Remarkably, nearly all sex chromosome drivers are found in two clades, Rodentia and Diptera. Although very little is known about the molecular and cellular mechanisms of drive, epigenetic processes such as chromatin regulation could be involved in many instances. Yet, its evolutionary consequences are far-reaching, from the evolution of mating systems and sex determination to the emergence of new species.

Indexed as

Models, GeneticSex ChromosomesAnimalsDipteraEvolution, MolecularExtinction, BiologicalGenetic SpeciationRodentiaSex Determination ProcessesSex FactorsSex Ratio

Identifiers

PMID25524548
PMCPMC4315933
OpenAlexW2095804125

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.