Evidence map›Paper›PMID 25524303›Full record

ArticleInternational journal of surgery case reports2015

Peritonitis secondary to spontaneous perforation of a primary gastrointestinal stromal tumour of the small intestine: A case report and a literature review.

Mario Alessiani, Marco Gianola, Sabina Rossi, Vittorio Perfetti, Piero Serra, Daniela Zelaschi, Enzo Magnani, Lorenzo Cobianchi

Open access · goldAbstract read
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Article in International journal of surgery case reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Mario AlessianiDepartment of General Surgery, Varzi Hospital, Italy; Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Italy.
Marco GianolaDepartment of General Surgery, Varzi Hospital, Italy.
Sabina RossiRadiology Service, Voghera Hospital, Italy.
Vittorio PerfettiDepartment of Oncology, IRCCS San Matteo Hospital Foundation, Pavia, Italy. Electronic address: v.perfetti@smatteo.pv.it.
Piero SerraDepartment of General Surgery, Varzi Hospital, Italy. Electronic address: piero_serra@ospedali.pavia.it.
Daniela ZelaschiDepartment of General Surgery, Varzi Hospital, Italy. Electronic address: daniela_zelaschi@ospedali.pavia.it.
Enzo MagnaniDepartment of General Surgery, Varzi Hospital, Italy. Electronic address: enzo_magnani@ospedali.pavia.it.
Lorenzo CobianchiUnit of General Surgery 1, IRCCS San Matteo Hospital Foundation, Pavia, Italy; Department of Clinical, Surgical, Diagnostic and Paediatric Sciences, University of Pavia, Italy. Electronic address: l.cobianchi@smatteo.pv.it.
University of Pavia · ITUniversity Hospital Foundation · CAOspedale Civile di Voghera · ITOspedale San Paolo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionA few cases of acute abdomen caused by perforation of small-intestinal gastrointestinal stromal tumours (GISTs) have been reported in the literature. PRESENTATION OF CASE: Together with a review of the published cases, here we report a case of an elderly patient with peritonitis due to spontaneous perforation of a GIST of the jejunum. An 82-year-old man was admitted to the emergency unit of our hospital with fever and severe abdominal pain. An abdominal enhanced computed tomography scan detected a 6cm solid mass in the left upper quadrant adherent to a jejunal loop and surrounded by free fluid and free air. Due to the radiological features of the mass, the diagnosis of a perforation of a GIST arising from the jejunum wall was suspected. The patient underwent emergency laparotomy. Intraoperative findings confirmed diffuse peritonitis secondary to jejunal tumour perforation. A segmental resection of the jejunum containing the mass was performed followed by a mechanical end-to-side anastomosis. The histopathologic examination of the mass confirmed the diagnosis of a perforated GIST of the small intestine (high-risk category). The post-operative course was uneventful and the patient was treated with adjuvant imatinib therapy. DISCUSSION: Twenty-one other cases of spontaneous perforation of small intestine GISTs are reported in the literature and are summarized in the present review.

conclusionThe described case is the tip of the iceberg and spontaneous rupture or perforation of GISTs are a far more frequent first presentation of this rare tumour.

Indexed as

Gastrointestinal stromal tumoursPeritonitisSmall intestine

Identifiers

PMID25524303
PMCPMC4334641
OpenAlexW2138913540

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.