Evidence map›Paper›PMID 25524085›Full record

ArticleBipolar disorders2015

The longitudinal course of sleep timing and circadian preferences in adults with bipolar disorder.

Mohammad A Seleem, John A Merranko, Tina R Goldstein, Benjamin I Goldstein, David A Axelson, David A Brent, Vishwajit L Nimgaonkar, Rasim S Diler, Dara J Sakolsky, David J Kupfer and 1 more

Abstract readComparative Study
In one paragraph

Article in Bipolar disorders, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
  5. Bipolar Disorder, Circadian Rhythm and Clock Genes.Clinical psychopharmacology and neuroscience : the official scientific journal of the Korean College of Neuropsychopharmacology · 2024
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Evaluating endophenotypes for bipolar disorder.International journal of bipolar disorders · 2021
    Review
  11. Sleep and Circadian Rhythm Disorder in Bipolar Affective Disorder.Current topics in behavioral neurosciences · 2021
    Article
  12. Review
  13. Review
  14. Review
  15. Review
  16. Article
  17. Chronotype and Mental Health: Recent Advances.Current psychiatry reports · 2018
    Review
  18. Article
  19. Genetic Influences on Evening Preference Overlap with Those for Bipolar Disorder in a Sample of Mexican Americans and American Indians.Twin research and human genetics : the official journal of the International Society for Twin Studies · 2017
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Mohammad A SeleemDepartment of Psychiatry and Neurology, Tanta University, Tanta, Egypt.
John A MerrankoDepartment of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Tina R GoldsteinDepartment of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Benjamin I GoldsteinDepartment of Psychiatry, Sunnybrook Health Sciences Centre, University of Toronto Faculty of Medicine, Toronto, ON, Canada.
David A AxelsonDepartment of Psychiatry, Nationwide Children's Hospital and The Ohio State College of Medicine, Columbus, OH, USA.
David A BrentDepartment of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Vishwajit L NimgaonkarDepartment of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Rasim S DilerDepartment of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Dara J SakolskyDepartment of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
David J KupferDepartment of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.
Boris BirmaherDepartment of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA.

Funding

University of Pittsburgh Clinical and Translational Science InstituteUL1TR000005 · NCATS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E · 2012 to 2015
$50.8M
Children of Bipolar Parents: A High Risk Follow Up Study (also known as Bipolar Offspring Study - BIOS)R01MH060952 · NIMH · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI BIRMAHER, BORIS, PHILLIPS, MARY LOUISE · 2001 to 2020
$20.4M
Psychiatric research infrastructure for intervention and implementation in India – TEAMSD43TW009114 · FIC · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI Smita N Deshpande, Mary Elizabeth Hawk · 2014 to 2026
$3.2M
FIC NIH HHS D43 TW009114NCATS NIH HHS UL1 TR000005NIMH NIH HHS #MH-060952NIMH NIH HHS R01 MH060952
6 · The paper itself

Abstract

objectivesTo study the longitudinal course of sleep timing and circadian preferences in individuals with bipolar disorder (BP) compared to individuals with non-BP psychopathology and healthy controls.

methodsIndividuals with bipolar I and bipolar II disorder (n = 257), non-BP psychopathology (n = 105), and healthy controls (n = 55) (mean age 40.2 years, 21.3% male, 85.1% Caucasian) were followed on average every 27 months for a mean of four years. Sleep timing parameters and circadian preference were reported using the Sleep Timing Questionnaire and The Composite Scale for Morningness. Group comparisons were adjusted for multiple comparisons and between-group differences in demographic variables and psychopharmacological treatment.

resultsRegardless of their current mood state, individuals with BP showed more sleep onset latency (SOL), wakening after sleep onset (WASO), and evening preference in comparison to both individuals with non-BP psychopathology and healthy controls. Individuals with BP also showed less stability of bed and awakening times in comparison to the other two groups, though these results were dependent on mood state. Non-BP individuals only showed more WASO and less stability in bed and awakening times before work/school days than healthy controls. Adjusting for comorbid disorders yielded similar results. Within-group analyses found little to no effect of time and BP subtype on sleep timing and circadian preference.

conclusionsDisturbances of sleep timing are prominent in individuals with BP. These disturbances are worse during mood episodes, but still apparent during euthymic periods. Evening preference was not associated with polarity type, or mood state in BP, suggesting that this characteristic may be a trait marker.

Indexed as

AdultBipolar DisorderCircadian RhythmComorbidityCross-Sectional StudiesFemaleHumansLongitudinal StudiesMaleMiddle AgedReference ValuesSleep Disorders, Circadian RhythmSurveys and Questionnairesbipolar disordercircadianeveningnessmorningnesssleep

Identifiers

PMID25524085
PMCPMC4458164

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.