Evidence map›Paper›PMID 25523935›Full record

ReviewProteomics. Clinical applications2015

Proteomics in the investigation of HIV-1 interactions with host proteins.

Ming Li

Abstract readReview
In one paragraph

Review in Proteomics. Clinical applications, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Host directed therapies: COVID-19 and beyond.Current research in pharmacology and drug discovery · 2021
    Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Ming LiLaboratory of Retrovirology, Division of Infectious Diseases, Department of Medicine, Alpert Medical School of Brown University, Providence, RI, USA.

Funding

Translational ScienceP30AI042853 · NIAID · MIRIAM HOSPITAL · PI LARRY K BROWN · 1998 to 2026
$51.7M
Statistics and Data Management P20GM104317 · NIGMS · UNIVERSITY OF RHODE ISLAND · PI FAST, LOREN · 2013 to 2017
$9.8M
Reproductive Hormones and their impact on HIV-1 acquisitionR01HD072693 · NICHD · RHODE ISLAND HOSPITAL · PI CU-UVIN, SUSAN, GUPTA, PHALGUNI · 2012 to 2016
$2.3M
Studies in HIV-1 Pathogenesis and TransmissionK24HD080539 · NICHD · RHODE ISLAND HOSPITAL · PI RAMRATNAM, BHARAT · 2014 to 2018
$807k
NIAID NIH HHS P30 AI042853NICHD NIH HHS K24 HD080539NICHD NIH HHS R01 HD072693NIGMS NIH HHS P20 GM104317NIGMS NIH HHS P20GM104317
6 · The paper itself

Abstract

Productive HIV-1 infection depends on host machinery, including a broad array of cellular proteins. Proteomics has played a significant role in the discovery of HIV-1 host proteins. In this review, after a brief survey of the HIV-1 host proteins that were discovered by proteomic analyses, I focus on analyzing the interactions between the virion and host proteins, as well as the technologies and strategies used in those proteomic studies. With the help of proteomics, the identification and characterization of HIV-1 host proteins can be translated into novel antiretroviral therapeutics.

Indexed as

BiomarkersHIV-1HIV InfectionsHost-Pathogen InteractionsHumansProteomeProteomicsBiomarkersProteomeCellular factorHIV-1Host proteinMSViral protein

Identifiers

PMID25523935
PMCPMC4424045

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.