Evidence map›Paper›PMID 25523604›Full record

Trial reportOdontology2016

Clinical effect of locally delivered gel containing green tea extract as an adjunct to non-surgical periodontal treatment.

Kanyawat Rattanasuwan, Supanee Rassameemasmaung, Vanida Sangalungkarn, Chulaluk Komoltri

Registry-linked trialAbstract readClinical Trial
PubMed Publisher
In one paragraph

Trial report in Odontology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00918060 (Clinical Effects of Locally-delivered Gel Containing Camella Sinensis Extracts), which is not on this map. Cited by 20 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 5 pooled it
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00918060 phase2unknown statusnot on this map

Clinical Effects of Locally-delivered Gel Containing Camella Sinensis Extracts

TypeinterventionalSponsorMahidol UniversityRan2008 to 2010Enrolled48ConditionsPeriodontitisArmsCamella sinensis gel
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 5 syntheses or guidelines pooled it, 42 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Trial
  8. Trial
  9. Trial
  10. Application of injectable hydrogels in the treatment of periodontitis.Frontiers in bioengineering and biotechnology · 2026
    Review
  11. Review
  12. Review
  13. Review
  14. Review
  15. Article
  16. Review
  17. Impact of Green Tea (The Japanese dental science review · 2021
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Kanyawat RattanasuwanDepartment of Oral Medicine and Periodontology, Faculty of Dentistry, Mahidol University, Yothi Road, Ratchathewi, Bangkok, 10400, Thailand. kanyawat_3905@yahoo.com.
Supanee RassameemasmaungDepartment of Oral Medicine and Periodontology, Faculty of Dentistry, Mahidol University, Yothi Road, Ratchathewi, Bangkok, 10400, Thailand. supanee.ras@mahidol.ac.th.
Vanida SangalungkarnDepartment of Pharmacology, Faculty of Dentistry, Mahidol University, Yothi Road, Ratchathewi, Bangkok, 10400, Thailand. vanida.san@mahidol.ac.th.
Chulaluk KomoltriDivision of Clinical Epidemiology, Department of Research Development, Faculty of Medicine Siriraj Hosptial, Mahidol University, Bangkok, 10700, Thailand. chulaluk.kom@mahidol.ac.th.
Mahidol University · TH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

unlabelledGreen tea catechins had an in vitro antibacterial effect against periodontopathic bacteria and were able to inhibit destruction of the periodontal tissue. In this study, we aimed to evaluate the effect of locally delivered gel containing green tea extract as an adjunct to non-surgical periodontal treatment. Forty-eight subjects who had teeth with probing pocket depth of 5-10 mm were randomly allocated into the test or control group. Probing pocket depth, clinical attachment level, gingival index (GI), bleeding on probing (BOP) and full mouth plaque score were measured at baseline. Subjects received oral hygiene instruction, single episode of scaling and root planing and subgingival application of the green tea gel (test group) or the placebo gel (control group). The gel was repeatedly applied at 1 and 2 weeks later. The parameters were recorded again at the 1st, 3rd and 6th month after the last gel application. The results showed that all parameters were improved in both groups compared to baseline. The test group exhibited significantly higher reduction in BOP at the 3rd month (p = 0.003) and significantly lower GI at the 1st month (p < 0.001) and 3rd month (p < 0.001) when compared with the control group. Thus, green tea gel could provide a superior benefit in reducing bleeding on probing and gingival inflammation when used as an adjunct to non-surgical periodontal treatment. (

trial registrationMU-IRB 2008/153.0511, ClinicalTrials.gov NCT00918060).

Indexed as

TeaCatechinChronic PeriodontitisDental ScalingDouble-Blind MethodFemaleGelsHumansMaleMiddle AgedPeriodontal IndexPlant ExtractsRoot PlaningTreatment OutcomeCatechinGelsPlant ExtractsTeaCatechinsGreen teaLocal drug deliveryNon-surgical periodontal treatmentPeriodontal disease

Identifiers

PMID25523604
OpenAlexW2093705586

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.