Evidence map›Paper›PMID 25523111›Full record

ArticleClinical genetics2015

Genetic counselors' (GC) knowledge, awareness, understanding of clinical next-generation sequencing (NGS) genomic testing.

P M Boland, K Ruth, J M Matro, K L Rainey, C Y Fang, Y N Wong, M B Daly, M J Hall

Abstract read
In one paragraph

Article in Clinical genetics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Informed consent for genetic testing in hematology.Hematology. American Society of Hematology. Education Program · 2020
    Review
  7. Article
  8. Article
  9. The genetic background of Southern Iranian couples before marriage.Balkan journal of medical genetics : BJMG · 2016
    Article
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

P M BolandRoswell Park Cancer Institute, Department of Medicine, Medical Oncology, Buffalo, NY, USA.
K RuthFox Chase Cancer Center, Clinical Genetics, Philadelphia, PA, USA.
J M MatroFox Chase Cancer Center, Clinical Genetics, Philadelphia, PA, USA.
K L RaineyFox Chase Cancer Center, Clinical Genetics, Philadelphia, PA, USA.
C Y FangFox Chase Cancer Center, Clinical Genetics, Philadelphia, PA, USA.
Y N WongFox Chase Cancer Center, Clinical Genetics, Philadelphia, PA, USA.
M B DalyFox Chase Cancer Center, Clinical Genetics, Philadelphia, PA, USA.
M J HallFox Chase Cancer Center, Clinical Genetics, Philadelphia, PA, USA.
Fox Chase Cancer Center · USRoswell Park Comprehensive Cancer Center · US

Funding

WORD PROCESSING CENTER--COREP30CA006927 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI Margaret von Mehren · 1985 to 2026
$138.8M
NCI NIH HHS P30 CA006927NCI NIH HHS P30 CA006927-45
6 · The paper itself

Abstract

Genomic tests are increasingly complex, less expensive, and more widely available with the advent of next-generation sequencing (NGS). We assessed knowledge and perceptions among genetic counselors pertaining to NGS genomic testing via an online survey. Associations between selected characteristics and perceptions were examined. Recent education on NGS testing was common, but practical experience limited. Perceived understanding of clinical NGS was modest, specifically concerning tumor testing. Greater perceived understanding of clinical NGS testing correlated with more time spent in cancer-related counseling, exposure to NGS testing, and NGS-focused education. Substantial disagreement about the role of counseling for tumor-based testing was seen. Finally, a majority of counselors agreed with the need for more education about clinical NGS testing, supporting this approach to optimizing implementation.

Indexed as

AwarenessComprehensionGenetic CounselingKnowledgeAdultAgedEducation, ContinuingFemaleGenetic TestingHigh-Throughput Nucleotide SequencingHumansMaleMiddle AgedNeoplasmsProfessional CompetenceYoung Adultgenetic counselingnext-generation sequencingpreparedness

Identifiers

PMID25523111
PMCPMC4474774
OpenAlexW1604379927

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.