ReviewFly2014
The song of the old mother: reproductive senescence in female drosophila.
Review in Fly, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed.
- Seasonal evolution of Drosophila melanogaster abdominal pigmentation is associated with a multifarious selective landscape.Evolution; international journal of organic evolution · 2026Article
- Age-dependent mating dynamics, body size, and sex ratio in colonisedCurrent research in parasitology & vector-borne diseases · 2026Article
- Effects of insect longevity and drought conditions on aster leafhopper (Hemiptera: Cicadellidae) fecundity.Environmental entomology · 2025Article
- Olfactory inputs regulate Drosophila melanogaster oogenesis.The Journal of experimental biology · 2024Article
- Pharmacology of Aging:Aging biology · 2024Article
- Gene Protein Sequence Evolution Can Predict the Rapid Divergence of Ovariole Numbers in the Drosophila melanogaster Subgroup.Genome biology and evolution · 2024Article
- The roles of TGFβ and serotonin signaling in regulating proliferation of oocyte precursors and germline aging.bioRxiv : the preprint server for biology · 2024Article
- Article
- Ovarian aging in humans: potential strategies for extending reproductive lifespan.GeroScience · 2023Review
- Serotonergic signaling plays a deeply conserved role in improving oocyte quality.Developmental biology · 2023Article
- What do we mean by "aging"? Questions and perspectives revealed by studies in Drosophila.Mechanisms of ageing and development · 2023Article
- Investigating the unaccounted ones: insights on age-dependent reproductive loss in a viviparous fly.Frontiers in ecology and evolution · 2023Article
- Advanced maternal age has negative multigenerational impacts duringCurrent research in insect science · 2023Article
- Current Animal Model Systems for Ovarian Aging Research.Aging and disease · 2022Review
- Endosymbiotic Male-KillingApplied and environmental microbiology · 2022Article
- Phenotyping ofBiomolecules · 2022Review
- Drosophila melanogaster Stress Odorant (dSO) Displays the Characteristics of an Interspecific Alarm Cue.Journal of chemical ecology · 2021Article
- TheG3 (Bethesda, Md.) · 2020Article
- Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Among animals with multiple reproductive episodes, changes in adult condition over time can have profound effects on lifetime reproductive fitness and offspring performance. The changes in condition associated with senescence can be particularly acute for females who support reproductive processes from oogenesis through fertilization. The pomace fly Drosophila melanogaster is a well-established model system for exploring the physiology of reproduction and senescence. In this review, we describe how increasing maternal age in Drosophila affects reproductive fitness and offspring performance as well as the genetic foundation of these effects. Describing the processes underlying female reproductive senescence helps us understand diverse phenomena including population demographics, condition-dependent selection, sexual conflict, and transgenerational effects of maternal condition on offspring fitness. Understanding the genetic basis of reproductive senescence clarifies the nature of life-history trade-offs as well as potential ways to augment and/or limit female fertility in a variety of organisms.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.