ArticleMolecular and cellular biology1989
A 125-base-pair CEN6 DNA fragment is sufficient for complete meiotic and mitotic centromere functions in Saccharomyces cerevisiae.
Article in Molecular and cellular biology, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers.
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Who cites it
73 citing papers in PubMed.
- Context-dependent neocentromere activity in synthetic yeast chromosomeCell genomics · 2023Article
- Cryo-EM structure of the complete inner kinetochore of the budding yeast point centromere.Science advances · 2023Article
- DASH/Dam1 complex mutants stabilize ploidy in histone-humanized yeast by weakening kinetochore-microtubule attachments.The EMBO journal · 2023Article
- Cell cycle control of kinetochore assembly.Nucleus (Austin, Tex.) · 2022Review
- Recent insights into mechanisms preventing ectopic centromere formation.Open biology · 2021Review
- The unique kind of human artificial chromosome: Bypassing the requirement for repetitive centromere DNA.Experimental cell research · 2020Review
- Genetic and epigenetic effects on centromere establishment.Chromosoma · 2020Review
- Structures of CENP-C cupin domains at regional centromeres reveal unique patterns of dimerization and recruitment functions for the inner pocket.The Journal of biological chemistry · 2019Article
- Architecture of the CBF3-centromere complex of the budding yeast kinetochore.Nature structural & molecular biology · 2018Article
- Heterochromatin and RNAi regulate centromeres by protecting CENP-A from ubiquitin-mediated degradation.PLoS genetics · 2018Article
- Article
- Review
- Diatom centromeres suggest a mechanism for nuclear DNA acquisition.Proceedings of the National Academy of Sciences of the United States of America · 2017Article
- Centromeres Drive a Hard Bargain.Trends in genetics : TIG · 2017Review
- Ccp1 Homodimer Mediates Chromatin Integrity by Antagonizing CENP-A Loading.Molecular cell · 2016Article
- Refinement of the Diatom Episome Maintenance Sequence and Improvement of Conjugation-Based DNA Delivery Methods.Frontiers in bioengineering and biotechnology · 2016Article
- Accurate identification of centromere locations in yeast genomes using Hi-C.Nucleic acids research · 2015Article
- Ectopic centromere nucleation by CENP--a in fission yeast.Genetics · 2014Article
- The centromere: epigenetic control of chromosome segregation during mitosis.Cold Spring Harbor perspectives in biology · 2014Review
- DNA replication components as regulators of epigenetic inheritance--lesson from fission yeast centromere.Protein & cell · 2014Review
13 more citing papers are in PubMed but not listed here.
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4 authors.
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Abstract
Saccharomyces cerevisiae centromeres contain a conserved region ranging from 111 to 119 base pairs (bp) in length, which is characterized by the three conserved DNA elements CDEI, CDEII, and CDEIII. We isolated a 125-bp CEN6 DNA fragment (named ML CEN6) containing only these conserved elements and assayed it completely separated from its chromosomal context on circular minichromosomes and on a large linear chromosome fragment. The results show that this 125-bp CEN6 DNA fragment is by itself sufficient for complete mitotic and meiotic centromere functions.
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