Evidence map›Paper›PMID 25522148›Full record

ReviewPLoS pathogens2014

Unique features of HIV-1 spread through T cell virological synapses.

Raymond A Alvarez, Maria Ines Barría, Benjamin K Chen

Abstract readReview
In one paragraph

Review in PLoS pathogens, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
33citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

33 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Nonlytic Egress and Transmission in the Virus World.Annual review of biochemistry · 2025
    Review
  4. Virus-Induced Cell Fusion and Syncytia Formation.Results and problems in cell differentiation · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Raymond A AlvarezDivision of Infectious Disease, Department of Medicine, Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Maria Ines BarríaDivision of Infectious Disease, Department of Medicine, Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.
Benjamin K ChenDivision of Infectious Disease, Department of Medicine, Immunology Institute, Icahn School of Medicine at Mount Sinai, New York, New York, United States of America.

Funding

Imaging Virological Synapses During Parenteral HIV TransmissionDP1DA028866 · NIDA · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CHEN, BENJAMIN K · 2009 to 2013
$4.1M
Mechanisms of highly efficient HIV transfer at virological synapsesR01AI074420 · NIAID · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CHEN, BENJAMIN K · 2008 to 2012
$2.1M
Mechanisms of efficient HIV infection through T cell virological synapsesR01GM113885 · NIGMS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI CHEN, BENJAMIN K · 2014 to 2017
$1.7M
NIAID NIH HHS AI074420NIAID NIH HHS R01 AI074420NIDA NIH HHS DA028866NIDA NIH HHS DP1 DA028866NIGMS NIH HHS R01 GM113885
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Cell AdhesionCell CommunicationCell MovementHIV-1HIV InfectionsHumansImmunological SynapsesT-LymphocytesVirus Assembly

Identifiers

PMID25522148
PMCPMC4270788

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.