Evidence map›Paper›PMID 25521853›Full record

ReviewCancers2014

Dynamic changes in numbers and properties of circulating tumor cells and their potential applications.

Ju-Yu Tseng, Chih-Yung Yang, Shu-Ching Liang, Ren-Shyan Liu, Jeng-Kai Jiang, Chi-Hung Lin

Open access · goldAbstract readReview
In one paragraph

Review in Cancers, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 27 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Review
  5. Current status and future perspectives in HER2 positive advanced gastric cancer.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2022
    Review
  6. Article
  7. Human epidermal growth factor receptor 2 (HER2) in advanced gastric cancer: where do we stand?Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2021
    Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Circulating Cell-Free Tumour DNA in the Management of Cancer.International journal of molecular sciences · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Ju-Yu TsengInstitute of Microbiology and Immunology, School of Life Science, National Yang-Ming University, Taipei 11221, Taiwan. magic1304@gmail.com.
Chih-Yung YangDepartment of Education and Research, Taipei City Hospital, Taipei 10629, Taiwan. yc3636@hotmail.com.
Shu-Ching LiangInstitute of Microbiology and Immunology, School of Life Science, National Yang-Ming University, Taipei 11221, Taiwan. suejing1@yahoo.com.tw.
Ren-Shyan LiuMolecular and Genetic Imaging Core/Taiwan Mouse Clinic, Taipei 11529, Taiwan. rsliu@vghtpe.gov.tw.
Jeng-Kai JiangDivision of Colon & Rectal Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei 11217, Taiwan. jkjiang@vghtpe.gov.tw.
Chi-Hung LinInstitute of Microbiology and Immunology, School of Life Science, National Yang-Ming University, Taipei 11221, Taiwan. linch@ym.edu.tw.
National Yang Ming Chiao Tung University · TWTaipei Veterans General Hospital · TWNational Yang Ming Chiao Tung University · TWTaipei City Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circulating tumor cells (CTCs) can be detected in the blood of different types of early or advanced cancer using immunology-based assays or nucleic acid methods. The detection and quantification of CTCs has significant clinical utility in the prognosis of metastatic breast, prostate, and colorectal cancers. CTCs are a heterogeneous population of cells and often different from those of their respective primary tumor. Understanding the biology of CTCs may provide useful predictive information for the selection of the most appropriate treatment. Therefore, CTC detection and characterization could become a valuable tool to refine prognosis and serve as a "real-time biopsy" and has the potential to guide precision cancer therapies, monitor cancer treatment, and investigate the process of metastasis.

Identifiers

PMID25521853
PMCPMC4276972
OpenAlexW2051462651

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.