Evidence map›Paper›PMID 25521371›Full record

ArticleNeuron2014

Unveiling the secret lives of glutamate transporters: VGLUTs engage in multiple transport modes.

Alessio Accardi

Open access · bronzeAbstract readComment
In one paragraph

Article in Neuron, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 55% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Alessio AccardiDepartment of Anesthesiology, Department of Physiology and Biophysics, Department of Biochemistry, Weill Cornell Medical College, New York, NY 10065, USA. Electronic address: ala2022@med.cornell.edu.
Cornell University · US

Funding

Structure and function of chloride channels and transportersR01GM085232 · NIGMS · WEILL MEDICAL COLL OF CORNELL UNIV · PI ACCARDI, ALESSIO · 2009 to 2013
$1.7M
NIGMS NIH HHS R01 GM085232
6 · The paper itself

Abstract

Accumulation of glutamate in synaptic vesicles is mediated by vesicular glutamate transporters called VGLUTs. In the current issue of Neuron, Preobraschenski et al. (2014) show that the VGLUTs, in addition to transporting glutamate, also provide the conductances necessary to maintain the appropriate voltage and pH inside these vesicles.

Indexed as

AnimalsChloridesGlutamic AcidNeurotransmitter AgentsPotassiumSynaptic VesiclesVesicular Glutamate Transport Protein 1ChloridesGlutamic AcidNeurotransmitter AgentsPotassiumVesicular Glutamate Transport Protein 1

Identifiers

PMID25521371
PMCPMC7263376
OpenAlexW1998497353

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.