ArticleBMC medical informatics and decision making2014
Differentially private genome data dissemination through top-down specialization.
Article in BMC medical informatics and decision making, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed.
- Privacy-Enhancing Technologies in Biomedical Data Science.Annual review of biomedical data science · 2024Review
- Deep convolutional and conditional neural networks for large-scale genomic data generation.PLoS computational biology · 2023Article
- The evolving privacy and security concerns for genomic data analysis and sharing as observed from the iDASH competition.Journal of the American Medical Informatics Association : JAMIA · 2022Article
- Parallel and private generalized suffix tree construction and query on genomic data.BMC genomic data · 2022Article
- Privacy-Preserving Artificial Intelligence Techniques in Biomedicine.Methods of information in medicine · 2022Article
- Big Data Privacy in Biomedical Research.IEEE transactions on big data · 2020Article
- Privacy-preserving techniques of genomic data-a survey.Briefings in bioinformatics · 2019Review
- Protecting Genomic Data Privacy with Probabilistic Modeling.Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing · 2019Article
- Article
- Mechanisms to protect the privacy of families when using the transmission disequilibrium test in genome-wide association studies.Bioinformatics (Oxford, England) · 2017Article
- A community effort to protect genomic data sharing, collaboration and outsourcing.NPJ genomic medicine · 2017Review
- Genome privacy: challenges, technical approaches to mitigate risk, and ethical considerations in the United States.Annals of the New York Academy of Sciences · 2017Review
- SCOTCH: Secure Counting Of encrypTed genomiC data using a Hybrid approach.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2017Article
- Realizing privacy preserving genome-wide association studies.Bioinformatics (Oxford, England) · 2016Article
- HEALER: homomorphic computation of ExAct Logistic rEgRession for secure rare disease variants analysis in GWAS.Bioinformatics (Oxford, England) · 2016Article
- PREMIX: PRivacy-preserving EstiMation of Individual admiXture.AMIA ... Annual Symposium proceedings. AMIA Symposium · 2016Article
- PALME: PAtients Like My gEnome.AMIA Joint Summits on Translational Science proceedings. AMIA Joint Summits on Translational Science · 2016Article
- FORESEE: Fully Outsourced secuRe gEnome Study basEd on homomorphic Encryption.BMC medical informatics and decision making · 2015Article
- Privacy-preserving GWAS analysis on federated genomic datasets.BMC medical informatics and decision making · 2015Article
- A community assessment of privacy preserving techniques for human genomes.BMC medical informatics and decision making · 2014Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Advanced sequencing techniques make large genome data available at an unprecedented speed and reduced cost. Genome data sharing has the potential to facilitate significant medical breakthroughs. However, privacy concerns have impeded efficient genome data sharing. In this paper, we present a novel approach for disseminating genomic data while satisfying differential privacy. The proposed algorithm splits raw genome sequences into blocks, subdivides the blocks in a top-down fashion, and finally adds noise to counts to preserve privacy. The experimental results suggest that the proposed algorithm can retain certain data utility in terms of a high sensitivity.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.