Evidence map›Paper›PMID 25520557›Full record

ArticleIntegrative medicine insights2014

Randomized trial of hypnosis as a pain and symptom management strategy in adults with sickle cell disease.

Gwenyth R Wallen, Kimberly R Middleton, Nancy Ames, Alyssa T Brooks, Daniel Handel

Registry-linked trialOpen access · diamondAbstract read
In one paragraph

Article in Integrative medicine insights, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT00393250 (Hypnosis as a Pain and Symptom Management Strategy in Patients With Sickle Cell Disease), which is not on this map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT00393250 phase3completednot on this map

Hypnosis as a Pain and Symptom Management Strategy in Patients With Sickle Cell Disease

TypeinterventionalSponsorNational Institutes of Health Clinical Center (CC)Ran2007 to 2012Enrolled31ConditionsSickle Cell Disease, Pain ManagementArmsHypnosis, Control
3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Predictors and Correlates of Fatigue in Sickle Cell Disease Patients.International journal of hematology-oncology and stem cell research · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Gwenyth R WallenNational Institutes of Health Clinical Center, Bethesda, MD, USA.
Kimberly R MiddletonNational Institutes of Health Clinical Center, Bethesda, MD, USA.
Nancy AmesNational Institutes of Health Clinical Center, Bethesda, MD, USA.
Alyssa T BrooksNational Institutes of Health Clinical Center, Bethesda, MD, USA.
Daniel HandelDenver Health Medical Center, Denver, CO, USA.
University of Colorado Denver · US

Funding

Hypnosis as a Pain and Symptom Management Strategy in Patients w/Sickle Cell DiseZIACL001146 · CLC · CLINICAL CENTER · PI WALLEN, GWENYTH R · 2009 to 2021
$0k
6 · The paper itself

Abstract

unlabelledSickle cell disease (SCD) is the most common genetic disease in African-Americans, characterized by recurrent painful vaso-occlusive crises. Medical therapies for controlling or preventing crises are limited because of efficacy and/or toxicity. This is a randomized, controlled, single-crossover protocol of hypnosis for managing pain in SCD patients. Participants receive hypnosis from a trained hypnosis therapist followed by six weeks of self-hypnosis using digital media. Those in the control arm receive SCD education followed by a six-week waiting period before crossing over to the hypnosis arm of the study. Outcome measures include assessments of pain (frequency, intensity and quality), anxiety, coping strategies, sleep, depression, and health care utilization. To date, there are no published randomized, controlled trials evaluating the efficacy of hypnosis on SCD pain modulation in adults. Self-hypnosis for pain management may be helpful in modulating chronic pain, improving sleep quality, and decreasing use of narcotics in patients with SCD.

trial registrationClinicalTrials.gov: NCT00393250.

Indexed as

chronic painhypnosispain managementsickle cell diseasesleepsymptom management

Identifiers

PMID25520557
PMCPMC4219848
OpenAlexW2080434689

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.