Evidence map›Paper›PMID 25520452›Full record

ArticleJournal of clinical microbiology2015

Evaluation of the Cepheid Xpert C. difficile/Epi and meridian bioscience illumigene C. difficile assays for detecting Clostridium difficile ribotype 033 strains.

Grace O Androga, Alan M McGovern, Briony Elliott, Barbara J Chang, Timothy T Perkins, Niki F Foster, Thomas V Riley

Open access · greenAbstract readComparative StudyEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical microbiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 19 citations in OpenAlex.

  1. An Update onToxins · 2022
    Review
  2. Article
  3. Current knowledge on the laboratory diagnosis ofWorld journal of gastroenterology · 2017
    Review
  4. Article
  5. HumanJMM case reports · 2016
    Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Grace O AndrogaSchool of Pathology and Laboratory Medicine, The University of Western Australia, Crawley, Western Australia, Australia.
Alan M McGovernSchool of Pathology and Laboratory Medicine, The University of Western Australia, Crawley, Western Australia, Australia.
Briony ElliottSchool of Pathology and Laboratory Medicine, The University of Western Australia, Crawley, Western Australia, Australia.
Barbara J ChangSchool of Pathology and Laboratory Medicine, The University of Western Australia, Crawley, Western Australia, Australia.
Timothy T PerkinsSchool of Pathology and Laboratory Medicine, The University of Western Australia, Crawley, Western Australia, Australia.
Niki F FosterSchool of Pathology and Laboratory Medicine, The University of Western Australia, Crawley, Western Australia, Australia.
Thomas V RileySchool of Pathology and Laboratory Medicine, The University of Western Australia, Crawley, Western Australia, Australia Department of Microbiology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia thomas.riley@uwa.edu.au.
University of Western Australia · AUPathwest Laboratory Medicine · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Clostridium difficile PCR ribotype 033 (RT033) is found in the gastrointestinal tracts of production animals and, occasionally, humans. The illumigene C. difficile assay (Meridian Bioscience, Inc.) failed to detect any of 52 C. difficile RT033 isolates, while all strains signaled positive for the binary toxin genes but were reported as negative for C. difficile by the Xpert C. difficile/Epi assay (Cepheid).

Indexed as

RibotypingAnimalsBacteriological TechniquesClostridioides difficileClostridium InfectionsHumansMolecular Diagnostic TechniquesSensitivity and Specificity

Identifiers

PMID25520452
PMCPMC4390624
OpenAlexW2136047484

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.