Evidence map›Paper›PMID 25520436›Full record

ArticleJournal of neurophysiology2015

Long-range GABAergic neurons in the prefrontal cortex modulate behavior.

Christian Bravo-Rivera, Maria M Diehl, Ciorana Roman-Ortiz, Jose Rodriguez-Romaguera, Luis E Rosas-Vidal, Hector Bravo-Rivera, Kelvin Quiñones-Laracuente, Fabricio H Do-Monte

Abstract readComment
In one paragraph

Article in Journal of neurophysiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  5. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors.

Christian Bravo-RiveraDepartment of Psychiatry and Department of Anatomy & Neurobiology, University of Puerto Rico School of Medicine, San Juan, Puerto Rico.
Maria M DiehlDepartment of Psychiatry and Department of Anatomy & Neurobiology, University of Puerto Rico School of Medicine, San Juan, Puerto Rico.
Ciorana Roman-OrtizDepartment of Psychiatry and Department of Anatomy & Neurobiology, University of Puerto Rico School of Medicine, San Juan, Puerto Rico.
Jose Rodriguez-RomagueraDepartment of Psychiatry and Department of Anatomy & Neurobiology, University of Puerto Rico School of Medicine, San Juan, Puerto Rico.
Luis E Rosas-VidalDepartment of Psychiatry and Department of Anatomy & Neurobiology, University of Puerto Rico School of Medicine, San Juan, Puerto Rico.
Hector Bravo-RiveraDepartment of Psychiatry and Department of Anatomy & Neurobiology, University of Puerto Rico School of Medicine, San Juan, Puerto Rico.
Kelvin Quiñones-LaracuenteDepartment of Psychiatry and Department of Anatomy & Neurobiology, University of Puerto Rico School of Medicine, San Juan, Puerto Rico.
Fabricio H Do-MonteDepartment of Psychiatry and Department of Anatomy & Neurobiology, University of Puerto Rico School of Medicine, San Juan, Puerto Rico fabriciodomonte@gmail.com.

Funding

RISE Option III: MBRS RISE at the UPR Medical Sciences CampusR25GM061838 · NIGMS · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI CADILLA, CARMEN LYDIA · 2000 to 2021
$25.5M
BDNF-ergic circuits in extinction of active avoidanceR36MH106332 · NIMH · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI ROSAS-VIDAL, LUIS E. · 2014 to 2015
$81k
Neural circuits of platform avoidanceR36MH102968 · NIMH · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI BRAVO-RIVERA, CHRISTIAN EMMANUELL · 2014 to 2015
$80k
Role of OFC in Fear Extinction and DBSR36MH105039 · NIMH · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI RODRIGUEZ-ROMAGUERA, JOSE · 2014 to 2014
$40k
NIGMS NIH HHS GM061838NIGMS NIH HHS R25 GM061838NIMH NIH HHS MH102968NIMH NIH HHS MH105039NIMH NIH HHS MH106332NIMH NIH HHS R36 MH102968NIMH NIH HHS R36 MH106332
6 · The paper itself

Abstract

Cortical glutamatergic projections are extensively studied in behavioral neuroscience, whereas cortical GABAergic projections to downstream structures have been overlooked. A recent study by Lee and colleagues (Lee AT, Vogt D, Rubenstein JL, Sohal VS. J Neurosci 34: 11519-11525, 2014) used optogenetic and electrophysiological techniques to characterize a behavioral role for long-projecting GABAergic neurons in the medial prefrontal cortex. In this Neuro Forum, we discuss the potential implications of this study in several learning and memory models.

Indexed as

AnimalsAvoidance LearningFemaleGABAergic NeuronsMaleNeural PathwaysNucleus AccumbensPrefrontal Cortexamygdalaaversionavoidancestriatum

Identifiers

PMID25520436
PMCPMC4556857

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.