ArticleProceedings. Biological sciences2015
Macronutrients mediate the functional relationship between Drosophila and Wolbachia.
Article in Proceedings. Biological sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
56 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-analysis suggests the microbiome responds to Evolve and Resequence experiments in Drosophila melanogaster.BMC microbiology · 2021Pooled it
- Pervasive effects ofbioRxiv : the preprint server for biology · 2026Article
- Temperature-sensitive cytoplasmic incompatibility across divergent Wolbachia partly reflects cifB transcription, not endosymbiont density.Molecular biology and evolution · 2026Article
- Bacterial Symbionts Associated with Wild Tsetse Flies (Diptera: Glossinidae) in Sub-Saharan Africa: A Systematic Review and Meta-Analysis.Life (Basel, Switzerland) · 2026Review
- Phytoplasma infection induces changes in vibrational signals of Cacopsylla pyri: sex-specific shifts in frequency, amplitude, and timing.BMC zoology · 2026Article
- Temperature-sensitive cytoplasmic incompatibility across divergentbioRxiv : the preprint server for biology · 2026Article
- Impact of larval diet on fitness outcomes of Aedes aegypti mosquitoes infected with wAlbB and wMelM.Parasites & vectors · 2025Article
- Microbes and diet reshape the intestine via distinct cellular dynamics.bioRxiv : the preprint server for biology · 2025Article
- Extracellular microbes are required for mosquito development even in the presence of Wolbachia.PLoS neglected tropical diseases · 2025Article
- Nutritional Trade-Offs inBiology · 2025Article
- Understanding the role of trehalose in interactions betweenFrontiers in cellular and infection microbiology · 2025Review
- Effect of Microsporidia MB infection on the development and fitness of Anopheles arabiensis under different diet regimes.Parasites & vectors · 2024Article
- Optimum ratio of dietary protein and carbohydrate that maximises lifespan is shared among related insect species.Aging cell · 2024Article
- AntiviralmBio · 2024Article
- Article
- Wolbachia has subtle effects on thermal preference in highly inbred Drosophila melanogaster which vary with life stage and environmental conditions.Scientific reports · 2023Article
- wMel Wolbachia alters female post-mating behaviors and physiology in the dengue vector mosquito Aedes aegypti.Communications biology · 2023Article
- Nutrigonometry IV: Thales' theorem to measure the rules of dietary compromise in animals.Scientific reports · 2023Article
- Food provisioning to Pardosa spiders decreases the levels of tissue-resident endosymbiotic bacteria.Scientific reports · 2023Article
- Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Wolbachia are maternally inherited bacterial endosymbionts that naturally infect a diverse array of arthropods. They are primarily known for their manipulation of host reproductive biology, and recently, infections with Wolbachia have been proposed as a new strategy for controlling insect vectors and subsequent human-transmissible diseases. Yet, Wolbachia abundance has been shown to vary greatly between individuals and the magnitude of the effects of infection on host life-history traits and protection against infection is correlated to within-host Wolbachia abundance. It is therefore essential to better understand the factors that modulate Wolbachia abundance and effects on host fitness. Nutrition is known to be one of the most important mediators of host-symbiont interactions. Here, we used nutritional geometry to quantify the role of macronutrients on insect-Wolbachia relationships in Drosophila melanogaster. Our results show fundamental interactions between diet composition, host diet selection, Wolbachia abundance and effects on host lifespan and fecundity. The results and methods described here open a new avenue in the study of insect-Wolbachia relationships and are of general interest to numerous research disciplines, ranging from nutrition and life-history theory to public health.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.