Evidence map›Paper›PMID 25519850›Full record

ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2015

Comparison of the preference-based EQ-5D-5L and SF-6D in patients with end-stage renal disease (ESRD).

Fan Yang, Titus Lau, Evan Lee, A Vathsala, Kee Seng Chia, Nan Luo

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Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed, 3 pooled it
11.4field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 3 syntheses or guidelines pooled it, 79 citations in OpenAlex.

  1. Psychometric properties of the EQ-5D-5L: a systematic review of the literature.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2021
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  5. Mapping the Edmonton Symptom Assessment System-Revised: Renal to the EQ-5D-5L in patients with chronic kidney disease.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2022
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  8. Psychometric properties comparison of EQ-5D-Y-3L and CHU9D in children and adolescents across different BMI classifications in Jiangsu, China.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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  15. Psychometric performance of EQ-5D-5L and SF-6Dv2 in patients with lymphoma in China.The European journal of health economics : HEPAC : health economics in prevention and care · 2024
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  19. Comparative performance and mapping algorithms between EQ-5D-5L and SF-6Dv2 among the Chinese general population.The European journal of health economics : HEPAC : health economics in prevention and care · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Fan YangSaw Swee Hock School of Public Health, National University of Singapore, 12 Science Drive 2, MD 1, Singapore, 117549, Singapore.
Titus LauDivision of Nephrology, University Medicine Cluster, National University Health System, 1E Kent Ridge Road, NUHS Tower Block, Singapore, 119228, Singapore.
Evan LeeDivision of Nephrology, University Medicine Cluster, National University Health System, 1E Kent Ridge Road, NUHS Tower Block, Singapore, 119228, Singapore.
A VathsalaDivision of Nephrology, University Medicine Cluster, National University Health System, 1E Kent Ridge Road, NUHS Tower Block, Singapore, 119228, Singapore.
Kee Seng ChiaSaw Swee Hock School of Public Health, National University of Singapore, 12 Science Drive 2, MD 1, Singapore, 117549, Singapore.
Nan LuoSaw Swee Hock School of Public Health, National University of Singapore, 12 Science Drive 2, MD 1, Singapore, 117549, Singapore. nan_luo@nuhs.edu.sg.
National University Health System · SGNational University of Singapore · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe objective of this study was to compare the performance of the 5-level EuroQol 5-dimension (EQ-5D-5L) and the Short Form 6-dimension (SF-6D) instruments in assessing patients with end-stage renal disease (ESRD) in Singapore.

methodsIn a cross-sectional study, ESRD patients attending a tertiary hospital were interviewed using a battery of questionnaires including the EQ-5D-5L, the kidney disease quality of life instrument (KDQOL-36), and questions assessing dialysis history and socio-demographic characteristics. We reviewed patients' medical records for their clinical information. We assessed the construct validity of the EQ-5D-5L and SF-6D index scores and compared their ability to distinguish between patients differing in health status and the magnitude of between-group difference they quantified.

resultsOne hundred and fifty ESRD patients on dialysis (mean age, 60.1 years; female, 48.7%) participated in the study. Both EQ-5D-5L and SF-6D demonstrated satisfactory known-groups validity; the EQ-5D-5L was more sensitive to differences in clinical outcomes and the SF-6D was more sensitive to differences in health outcomes measured by KDQOL scales. The intraclass correlation coefficient between the measures was 0.36. The differences in the EQ-5D-5L index score for patients in better and worse health status were greater than those measured by the SF-6D index score.

conclusionsBoth EQ-5D-5L and SF-6D are valid instruments for assessing ESRD patients. However, the two preference-based measures cannot be used interchangeably and it appears that EQ-5D-5L would lead to more favorable cost-effectiveness results than SF-6D if they are used in economic evaluations of interventions for ESRD.

Indexed as

Health StatusPatient PreferenceQuality of LifeCross-Sectional StudiesFemaleHumansInterviews as TopicKidney Failure, ChronicMaleMiddle AgedReproducibility of ResultsSingaporeSocioeconomic FactorsSurveys and QuestionnairesTertiary Care CentersDiscriminative abilityEQ-5D-5LESRDSF-6D

Identifiers

PMID25519850
OpenAlexW2031064002

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.