Evidence map›Paper›PMID 25519786›Full record

ArticleThe international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease2015

Gaps in using bronchodilators, inhaled corticosteroids and influenza vaccine among 23 high- and low-income sites.

L Gnatiuc, A S Buist, B Kato, C Janson, N Aït-Khaled, R Nielsen, P A Koul, E Nizankowska-Mogilnicka, D Obaseki, L F Idolor and 3 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.4field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Review
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  9. Prevalence of chronic airflow limitation in Kashmir, North India: results from the BOLD study.The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease · 2016
    Article
  10. Indian guidelines for asthma: Adherence is the key.Lung India : official organ of Indian Chest Society · 2015
    Article
  11. Article
  12. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 8 countries.

L GnatiucNational Heart and Lung Institute, Imperial College, London, UK.
A S BuistOregon Health & Science University, Portland, Oregon, USA.
B KatoNational Heart and Lung Institute, Imperial College, London, UK.
C JansonRespiratory Medicine & Allergology, Department of Medical Sciences, Uppsala University, Uppsala, Sweden.
N Aït-KhaledInternational Union Against Tuberculosis and Lung Disease, Paris, France.
R NielsenInstitute of Medicine, University of Bergen, Bergen, Norway; Department of Thoracic Medicine, Haukeland University Hospital, Bergen, Norway.
P A KoulSheri Kashmir Institute of Medical Sciences, Srinagar, India.
E Nizankowska-MogilnickaDepartment of Internal Medicine, Jagiellonian University School of Medicine, Krakow, Poland.
D ObasekiObafemi Awolowo University, Ile-Ife, Nigeria.
L F IdolorDepartment of Pulmonary Medicine, Lung Centre of the Philippines, Quezon City, The Philippines.
I HarrabiFaculty of Medicine, Sousse, Tunisia.
P G J BurneyNational Heart and Lung Institute, Imperial College, London, UK.
BOLD Collaboration
Imperial College London · GBInternational Union Against Tuberculosis and Lung Disease · FRJagiellonian University · PLObafemi Awolowo University · NGOregon Health & Science University · USSher-i-Kashmir Institute of Medical Sciences · INUniversity of Sousse · TNUppsala University · SE

Funding

Wellcome Trust 085790Wellcome Trust 085790/Z/08/Z
6 · The paper itself

Abstract

backgroundIncreasing access to essential respiratory medicines and influenza vaccination has been a priority for over three decades. Their use remains low in low- and middle-income countries (LMICs), where little is known about factors influencing use, or about the use of influenza vaccination for preventing respiratory exacerbations.

methodsWe estimated rates of regular use of bronchodilators, inhaled corticosteroids and influenza vaccine, and predictors for use among 19 000 adults in 23 high-income countries (HICs) and LMIC sites.

resultsBronchodilators, inhaled corticosteroids and influenza vaccine were used significantly more in HICs than in LMICs, after adjusting for similar clinical needs. Although they are used more commonly by people with symptomatic or severe respiratory disease, the gap between HICs and LMICs is not explained by the prevalence of chronic obstructive pulmonary disease or doctor-diagnosed asthma. Site-specific factors are likely to influence use differently. The gross national income per capita for the country is a strong predictor for use of these treatments, suggesting that economics influence under-treatment.

conclusionWe still need a better understanding of determinants for the low use of essential respiratory medicines and influenza vaccine in low-income settings. Identifying and addressing these more systematically could improve the access and use of effective treatments.

Indexed as

Adrenal Cortex HormonesAgedAsthmaBronchodilator AgentsCross-Sectional StudiesFemaleHumansInfluenza VaccinesMaleMiddle AgedPovertyPrevalencePulmonary Disease, Chronic ObstructiveSocioeconomic FactorsSurveys and QuestionnairesVaccinationAdrenal Cortex HormonesBronchodilator AgentsInfluenza Vaccines

Identifiers

PMID25519786
PMCPMC4531306
OpenAlexW1993448460

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.