Evidence map›Paper›PMID 25519317›Full record

ArticleBMC proceedings2014

Admixture mapping analysis in the context of GWAS with GAW18 data.

Mengjie Chen, Can Yang, Cong Li, Lin Hou, Xiaowei Chen, Hongyu Zhao

Abstract read
In one paragraph

Article in BMC proceedings, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Review
  2. Review
  3. Frontiers in plant science · 2023
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mengjie ChenProgram in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.
Can YangDepartment of Biostatistics, Yale School of Public Health, Yale University, New Haven, CT 06520, USA.
Cong LiProgram in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.
Lin HouDepartment of Biostatistics, Yale School of Public Health, Yale University, New Haven, CT 06520, USA.
Xiaowei ChenProgram in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA.
Hongyu ZhaoProgram in Computational Biology and Bioinformatics, Yale University, New Haven, CT 06520, USA ; Department of Biostatistics, Yale School of Public Health, Yale University, New Haven, CT 06520, USA.

Funding

Yale University Clinical and Translational Science Award ProgramUL1TR000142 · NCATS · YALE UNIVERSITY · PI SHERWIN, ROBERT S · 2012 to 2015
$31.8M
GENETIC ANALYSIS OF COMMON DISEASES: AN EVALUATIONR01GM031575 · NIGMS · UNIVERSITY OF TEXAS RIO GRANDE VALLEY · PI ALMASY, LAURA A. · 1985 to 2016
$7.8M
NCATS NIH HHS UL1 TR000142NIGMS NIH HHS R01 GM031575
6 · The paper itself

Abstract

Admixture mapping is a disease-mapping strategy to identify disease susceptibility variants in an admixed population that is a result of mating between 2 historically separated populations differing in allele frequencies and disease prevalence. With the increasing availability of high-density genotyping data generated in genome-wide association studies, it is of interest to investigate how to apply admixture mapping in the context of the genome-wide association studies and how to adjust for admixture in association tests. In this study, we first evaluated 3 different local ancestry inference methods, LAMP, LAMP-LD, and MULTIMIX. Then we applied admixture mapping analysis based on estimated local ancestry. Finally, we performed association tests with adjustment for local ancestry.

Identifiers

PMID25519317
PMCPMC4143627

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.