ArticleEnvironmental health and toxicology2014
The role of chorion on toxicity of silver nanoparticles in the embryonic zebrafish assay.
Article in Environmental health and toxicology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed, 117 citations in OpenAlex.
- Article
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- Testing the effects of two different zebrafish exposure paradigms on transcriptomic-based chemical risk assessment using the flame retardant triphenyl phosphate.Toxicological sciences : an official journal of the Society of Toxicology · 2025Article
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- A Zebrafish Embryo Model to Screen Potential Therapeutic Compounds inMolecules (Basel, Switzerland) · 2024Article
- Size- and Shape-Dependent Interactions of Lipid-Coated Silver Nanoparticles: An Improved Mechanistic Understanding through Model Cell Membranes andChemical research in toxicology · 2024Article
- Developmental impacts and toxicological hallmarks of silver nanoparticles across diverse biological models.Environmental science and ecotechnology · 2024Review
- Dechorionated zebrafish embryos improve evaluation of nanotoxicity.Frontiers in toxicology · 2024Article
- Development Features on the Selection of Animal Models for Teratogenic Testing.Methods in molecular biology (Clifton, N.J.) · 2024Article
- Comparison of Pronase versus Manual Dechorionation of Zebrafish Embryos for Small Molecule Treatments.Journal of developmental biology · 2023Article
- Toxicological Aspects, Safety Assessment, and Green Toxicology of Silver Nanoparticles (AgNPs)-Critical Review: State of the Art.International journal of molecular sciences · 2023Review
- Roundup in the Reproduction of Crucian Carp (Animals : an open access journal from MDPI · 2022Article
- Calcium Chloride Toxicology for Food Safety Assessment Using Zebrafish (Comparative medicine · 2022Article
- Phototoxicity effects of NIR-irradiated cesium tungsten oxide (CsToxicology reports · 2022Article
- High throughput embryonic zebrafish test with automated dechorionation to evaluate nanomaterial toxicity.PloS one · 2022Article
- Mechanisms of Silver Nanoparticle Uptake by Embryonic Zebrafish Cells.Nanomaterials (Basel, Switzerland) · 2021Article
- Article
- Predictive Capability of QSAR Models Based on the CompTox Zebrafish Embryo Assays: An Imbalanced Classification Problem.Molecules (Basel, Switzerland) · 2021Article
- Perfluorooctanesulfonic Acid-Induced Toxicity on Zebrafish Embryos in the Presence or Absence of the Chorion.Environmental toxicology and chemistry · 2021Article
- In Vivo Toxicity Assessment of Chitosan-Coated Lignin Nanoparticles in Embryonic Zebrafish (Nanomaterials (Basel, Switzerland) · 2021Article
Corrections and comments
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Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesThis study was designed to investigate how the size- and surface coating-dependent toxicity of silver nanoparticles (AgNPs) is influenced by the presence and absence of the chorion in an embryonic zebrafish assay.
methodsNormal and dechorinated embryos were exposed to four different AgNPs, 20 or 110 nm in size, with polypyrrolidone (PVP) or citrate surface coatings in a standard zebrafish embryo medium (EM). This was then compared to a 62.5 μM calcium chloride (CaCl2) solution where agglomeration was controlled.
resultsEmbryonic toxicity in the absence of the chorion was greater than in its presence. The smaller 20 nm AgNPs were more toxic than the larger 110 nm AgNPs, regardless of the chorion and test media. However, surface coating affected toxicity, since PVPcoated AgNPs were more toxic than citrate-coated AgNPs; this was strongly affected by the presence of the chorion in both EM and CaCl2.
conclusionsOur results demonstrate the permeability function of the chorion on the size- and surface coating-dependent toxicity of AgNPs. Thereafter, careful experiment should be conducted to assess nanoparticle toxicity in zebrafish embryos.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.