Evidence map›Paper›PMID 25518819›Full record

ArticleClinical journal of gastroenterology2015

Cronkhite-Canada syndrome showing elevated levels of antinuclear and anticentromere antibody.

Seisuke Ota, Akinori Kasahara, Shoko Tada, Takehiro Tanaka, Sachio Umena, Haruka Fukatsu, Toshio Noguchi, Tadashi Matsumura

Abstract readCase Reports
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In one paragraph

Article in Clinical journal of gastroenterology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Cronkhite-Canada Syndrome: A Case Report.JNMA; journal of the Nepal Medical Association · 2022
    Article
  9. Aplastic Anemia in a Patient with Cronkhite-Canada Syndrome.Internal medicine (Tokyo, Japan) · 2021
    Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Seisuke OtaDepartment of Internal Medicine, Himeji St. Mary Hospital, Himeji, Japan, seisukeota@yahoo.co.jp.
Akinori Kasahara
Shoko Tada
Takehiro Tanaka
Sachio Umena
Haruka Fukatsu
Toshio Noguchi
Tadashi Matsumura

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 56-year-old female initially visited an otorhinolaryngologist because of an impaired sense of taste in September, 2010 and was referred to our facility in October, 2010. She was diagnosed with Basedow's disease for which she underwent subtotal thyroidectomy in 1984 and arthritis involving multiple joints, primarily affecting her hands. In addition, the anticentromere antibody (ACA) level was markedly high. On physical examination, alopecia as well as hyperpigmentation of the dorsum of the hands and back was observed. Dystrophic changes of the fingernails and a bilateral thumb abduction deformity were observed. Antinuclear antibodies were elevated. Gastrointestinal endoscopy and colonoscopy revealed the mucosa carpeted with strawberry-like polypoid lesions. Histopathological examination of the biopsied specimen of the stomach revealed a corkscrew-like appearance. Thus, the patient was diagnosed with Cronkhite-Canada syndrome (CCS). She admitted to our hospital in November, 2010. Oral prednisolone was administered with success. In July, 2012, her antimitochondrial M2 antibody level was elevated. To the best of our knowledge, the present case is the first patient with CCS, a history of Basedow's disease, and elevated levels of ACA and antimitochondrial M2 antibody. We consider the present case suggests CCS could be caused by immunological abnormality.

Indexed as

Antibodies, AntinuclearAnti-Inflammatory AgentsArthritisFemaleGraves DiseaseHumansIntestinal PolyposisMiddle AgedPrednisoloneAntibodies, Antinuclearanticentromere antibodyAnti-Inflammatory AgentsPrednisolone

Identifiers

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.