ArticleClinics (Sao Paulo, Brazil)2014
Total IgE plasma levels vary according to gender and age in Brazilian patients with allergic rhinitis.
Article in Clinics (Sao Paulo, Brazil), 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 28 citations in OpenAlex.
- Prevalence of allergic diseases and evaluation of total IgE and blood eosinophils as diagnostic biomarkers in Colombia, a tropical country.The World Allergy Organization journal · 2026Article
- Mouse Model of STAT3 Mutation Resulting in Job's Syndrome Diverges from Human Pathology.International journal of molecular sciences · 2025Article
- Impact of Early-Life Microbiota on Immune System Development and Allergic Disorders.Biomedicines · 2025Review
- The relationship between prebiotic intake and allergic rhinitis.Laryngoscope investigative otolaryngology · 2023Article
- K-means cluster analysis of characteristic patterns of allergen in different ages: Real life study.Clinical and translational allergy · 2023Article
- Article
- Insulin Resistance Increases Serum Immunoglobulin E Sensitization in Premenopausal Women.Diabetes & metabolism journal · 2021Article
- Prevalence and clinical characteristics of allergic rhinitis in the elderly Korean population.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2020Article
- Matters of life and death: How estrogen and estrogen receptor binding to the immunoglobulin heavy chain locus may influence outcomes of infection, allergy, and autoimmune disease.Cellular immunology · 2019Review
- Determination of Serum IgE and Eosinophils as a Diagnostic Indicator in Allergic Rhinitis.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2019Article
- Immunological Processes Driving IgE Sensitisation and Disease Development in Males and Females.International journal of molecular sciences · 2018Review
- Androgen-Induced Immunosuppression.Frontiers in immunology · 2018Review
- A 10-year retrospective study of alterative aeroallergens sensitization spectrum in urban children with allergic rhinitis.Therapeutics and clinical risk management · 2018Article
- Prevalence of Self-reported Allergic Diseases and IgE Levels: A 2010 KNHANES Analysis.Allergy, asthma & immunology research · 2017Article
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveAllergic rhinitis is a disease that affects the upper airways and causes inflammation of the nasal mucosa and it is mediated by IgE antibodies produced after sensitization to environmental allergens. Previous reports have indicated that this disease affects males more often than females. The objective of this study was to verify whether total IgE plasma levels vary between genders in patients suffering from allergic rhinitis.
methodsA total of 171 adult patients suffering from allergic rhinitis (55 males and 116 females) were enrolled. Total IgE plasma levels were determined using commercial kits, with 140 IU/mL considered as a reference value. The mean total IgE plasma levels were compared according to gender and age.
resultsThe mean age of the overall patient group with allergic rhinitis was 38.4 ± 19.0 years and a significant difference in age was observed between genders (males: 32.2 ± 17.8 years; females: 41.4 ± 18.9 years; p=0.0027). Additionally, the mean total IgE plasma levels were higher in males (413.0 ± 143.0 IU/mL) than in females (147.9 ± 98.0 IU/mL) (p<0.0001). These differences persisted even when males and females were stratified by age (up to or older than 20 years of age).
conclusionsIn conclusion, total IgE plasma levels are higher in young adult males than in females suffering from allergic rhinitis. Evaluating total IgE plasma levels can be useful to identify patients at risk of allergic rhinitis in areas with low industrial pollution.
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