Evidence map›Paper›PMID 25518002›Full record

ArticleLangmuir : the ACS journal of surfaces and colloids2015

Caging metal ions with visible light-responsive nanopolymersomes.

Julianne C Griepenburg, Nimil Sood, Kevin B Vargo, Dewight Williams, Jeff Rawson, Michael J Therien, Daniel A Hammer, Ivan J Dmochowski

Abstract read
In one paragraph

Article in Langmuir : the ACS journal of surfaces and colloids, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.0field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Engineering Polymersomes for Diagnostics and Therapy.Advanced healthcare materials · 2018
    Review
  6. Ruthenium-Crosslinked Hydrogels with Rapid, Visible-Light Degradation.Chemistry (Weinheim an der Bergstrasse, Germany) · 2018
    Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Julianne C GriepenburgDepartment of Chemistry, University of Pennsylvania , 231 South 34th Street, Philadelphia, Pennsylvania 19104, United States.
Nimil Sood
Kevin B Vargo
Dewight Williams
Jeff Rawson
Michael J Therien
Daniel A Hammer
Ivan J Dmochowski
University of Pennsylvania · USDuke University · US

Funding

Oligonucleotides for turning genes on and off with lightR01GM083030 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI DMOCHOWSKI, IVAN JULIAN · 2008 to 2017
$3.0M
LEICA TCS SP2 AOBS UV CONFOCAL SYSTEM: EMBRYO DEVELOPMENTS10RR021113 · NCRR · UNIVERSITY OF PENNSYLVANIA · PI DMOCHOWSKI, IVAN JULIAN · 2005 to 2005
$497k
NCRR NIH HHS 1S10RR021113NCRR NIH HHS S10 RR021113NIGMS NIH HHS R01 GM083030
6 · The paper itself

Abstract

Polymersomes are bilayer vesicles that self-assemble from amphiphilic diblock copolymers, and provide an attractive system for the delivery of biological and nonbiological molecules due to their environmental compatibility, mechanical stability, synthetic tunability, large aqueous core, and hyperthick hydrophobic membrane. Herein, we report a nanoscale photoresponsive polymersome system featuring a meso-to-meso ethyne-bridged bis[(porphinato)zinc] (PZn2) fluorophore hydrophobic membrane solute and dextran in the aqueous core. Upon 488 nm irradiation in solution or in microinjected zebrafish embryos, the polymersomes underwent deformation, as monitored by a characteristic red-shifted PZn2 emission spectrum and confirmed by cryo-TEM. The versatility of this system was demonstrated through the encapsulation and photorelease of a fluorophore (FITC), as well as two different metal ions, Zn(2+) and Ca(2+).

Indexed as

LightCalciumCryoelectron MicroscopyHydrophobic and Hydrophilic InteractionsPolymersZincCalciumPolymersZinc

Identifiers

PMID25518002
PMCPMC4303334
OpenAlexW2318328100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.