ArticleAstrobiology2015
Spaceflight induces specific alterations in the proteomes of Arabidopsis.
Article in Astrobiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 1 synthesis or guideline pooled it, 66 citations in OpenAlex.
- Functional Meta-Analysis of the Proteomic Responses of Arabidopsis Seedlings to the Spaceflight Environment Reveals Multi-Dimensional Sources of Variability across Spaceflight Experiments.International journal of molecular sciences · 2023Pooled it
- Exploring plant responses to altered gravity for advancing space agriculture.Plant communications · 2025Review
- Transcriptomic dynamics in the transition from ground to space are revealed by Virgin Galactic human-tended suborbital spaceflight.NPJ microgravity · 2023Article
- Glycome profiling and immunohistochemistry uncover changes in cell walls of Arabidopsis thaliana roots during spaceflight.NPJ microgravity · 2023Article
- Article
- Conserved plant transcriptional responses to microgravity from two consecutive spaceflight experiments.Frontiers in plant science · 2023Article
- Integrative transcriptomics and proteomics profiling ofFrontiers in plant science · 2023Article
- Lipid Rafts and Plant Gravisensitivity.Life (Basel, Switzerland) · 2022Review
- Mission Architecture Using the SpaceX Starship Vehicle to Enable a Sustained Human Presence on Mars.New space · 2022Article
- Combining Proteomics and Metabolomics to Analyze the Effects of Spaceflight on Rice Progeny.Frontiers in plant science · 2022Article
- Molecular Basis to Integrate Microgravity Signals into the Photoperiodic Flowering Pathway inInternational journal of molecular sciences · 2021Article
- Network Analysis of Gene Transcriptions ofGenes · 2021Article
- Epigenomic RegulatorsFrontiers in plant science · 2021Article
- Metabolomics Analysis in Different Development Stages on SP0 Generation of Rice Seeds After Spaceflight.Frontiers in plant science · 2021Article
- Article
- Spaceflight induces novel regulatory responses in Arabidopsis seedling as revealed by combined proteomic and transcriptomic analyses.BMC plant biology · 2020Article
- Test ofFrontiers in plant science · 2020Article
- Root Skewing-Associated Genes Impact the Spaceflight Response ofFrontiers in plant science · 2020Article
- Epigenomics in an extraterrestrial environment: organ-specific alteration of DNA methylation and gene expression elicited by spaceflight in Arabidopsis thaliana.BMC genomics · 2019Article
- A member of the CONSTANS-Like protein family is a putative regulator of reactive oxygen species homeostasis and spaceflight physiological adaptation.AoB PLANTS · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Life in spaceflight demonstrates remarkable acclimation processes within the specialized habitats of vehicles subjected to the myriad of unique environmental issues associated with orbital trajectories. To examine the response processes that occur in plants in space, leaves and roots from Arabidopsis (Arabidopsis thaliana) seedlings from three GFP reporter lines that were grown from seed for 12 days on the International Space Station and preserved on orbit in RNAlater were returned to Earth and analyzed by using iTRAQ broad-scale proteomics procedures. Using stringent criteria, we identified over 1500 proteins, which included 1167 leaf proteins and 1150 root proteins we were able to accurately quantify. Quantification revealed 256 leaf proteins and 358 root proteins that showed statistically significant differential abundance in the spaceflight samples compared to ground controls, with few proteins differentially regulated in common between leaves and roots. This indicates that there are measurable proteomics responses to spaceflight and that the responses are organ-specific. These proteomics data were compared with transcriptome data from similar spaceflight samples, showing that there is a positive but limited relationship between transcriptome and proteome regulation of the overall spaceflight responses of plants. These results are discussed in terms of emergence understanding of plant responses to spaceflight particularly with regard to cell wall remodeling, as well as in the context of deriving multiple omics data sets from a single on-orbit preservation and operations approach.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.