ArticlePloS one2014
Human brucellosis in Maghreb: existence of a lineage related to socio-historical connections with Europe.
Article in PloS one, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Prevalence of Brucellosis in Small Ruminants in Africa from 2000 to 2025: A Systematic Review and Meta-Analysis.Veterinary sciences · 2026Review
- A Genomic Characterization of ClinicalMicroorganisms · 2025Article
- Animal Brucellosis in Egypt: Review on Evolution, Epidemiological Situation, PrevalentMicroorganisms · 2025Review
- Seroprevalence of brucellosis in sheep and goats from Al Jufrah district in Libya.The Pan African medical journal · 2024Article
- Serological, phenotypic and molecular characterization of brucellosis in small ruminants in northern Algeria.Frontiers in microbiology · 2024Article
- Seroprevalence of human brucellosis in Morocco and associated risk factors.Veterinary world · 2022Article
- Brucellosis in small ruminant: seroprevalence, risk factors, and distribution in the southeast of Algeria.Tropical animal health and production · 2022Article
- Erratum to "Evolution of animal and human brucellosis in Algeria: a mini narrative review: Anerni n tawla n Malṭa n yiɣersiwen d yimdanen di Lezzayer: tasɣunt tanalasant tilemẓit" [New Microbes and New Infections March 46C, (2022) 100975].New microbes and new infections · 2022Article
- Evolution of animal and human brucellosis in Algeria: a mini narrative review.New microbes and new infections · 2022Review
- Seroprevalence and Risk Factors of Brucellosis in Ruminants in Dhofar Province in Southern Oman.Veterinary medicine international · 2022Article
- Investigation of a human brucellosis outbreak in Douz, Tunisia, 2018.Epidemiology and health · 2022Article
- Animal and Human Brucellosis in Pakistan.Frontiers in public health · 2021Review
- Evolutionary history and current distribution of the West Mediterranean lineage ofMicrobial genomics · 2020Article
- MLVA-16 Genotyping ofPathogens (Basel, Switzerland) · 2020Article
- Scoping review of brucellosis in Cameroon: Where do we stand, and where are we going?PloS one · 2020Article
- Serological and histopathological investigation of brucellosis in cattle in Medea region, Northern Algeria.Veterinary world · 2019Article
- Brucellosis in Colombia: Current Status and Challenges in the Control of an Endemic Disease.Frontiers in veterinary science · 2019Review
- Knowledge of pastoralists on livestock diseases and exposure assessment to brucellosis within rural and peri-urban areas in Kajiado, Kenya.F1000Research · 2019Article
- A Case Report of Pediatric Brucellosis in an Algerian Immigrant.Open forum infectious diseases · 2017Article
- Article
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7 authors.
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Abstract
Despite control/eradication programs, brucellosis, major worldwide zoonosis due to the Brucella genus, is endemic in Northern Africa and remains a major public health problem in the Maghreb region (Algeria/Morocco/Tunisia). Brucella melitensis biovar 3 is mostly involved in human infections and infects mainly small ruminants. Human and animal brucellosis occurrence in the Maghreb seems still underestimated and its epidemiological situation remains hazy. This study summarizes official data, regarding Brucella melitensis infections in Algeria, from 1989 to 2012, with the purpose to provide appropriate insights concerning the epidemiological situation of human and small ruminant brucellosis in Maghreb. Algeria and Europe are closely linked for historical and economical reasons. These historical connections raise the question of their possible impact on the genetic variability of Brucella strains circulating in the Maghreb. Other purpose of this study was to assess the genetic diversity among Maghreb B. melitensis biovar 3 strains, and to investigate their possible epidemiological relationship with European strains, especially with French strains. A total of 90 B. melitensis biovar 3 Maghreb strains isolated over a 25 year-period (1989-2014), mainly from humans, were analysed by MLVA-16. The obtained results were compared with genotypes of European B. melitensis biovar 3 strains. Molecular assays showed that Algerian strains were mainly distributed into two distinct clusters, one Algerian cluster related to European sub-cluster. These results led to suggest the existence of a lineage resulting from socio-historical connections between Algeria and Europe that might have evolved distinctly from the Maghreb autochthonous group. This study provides insights regarding the epidemiological situation of human brucellosis in the Maghreb and is the first molecular investigation regarding B. melitensis biovar 3 strains circulating in the Maghreb.
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