ArticleEuropean journal of pediatrics1989
Abdominal, retroperitoneal and sacrococcygeal tumours of the newborn and the very young infant. Report from the Kiel Paediatric Tumour Registry.
Article in European journal of pediatrics, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Who cites it
7 citing papers in PubMed, 22 citations in OpenAlex.
- Retrospective Evaluation of Childhood Germ Cell Tumors: A Single-Center Experience.Children (Basel, Switzerland) · 2025Article
- Germ cell tumors in children.Virchows Archiv : an international journal of pathology · 2025Review
- Extragonadal germ cell tumors: Not just a matter of location. A review about clinical, molecular and pathological features.Cancer medicine · 2019Review
- Gonadal and extragonadal germ cell tumours in the United States, 1973-2007.International journal of andrology · 2012Article
- Congenital sacrococcygeal PNET and chemotherapy.Indian journal of medical and paediatric oncology : official journal of Indian Society of Medical & Paediatric Oncology · 2012Article
- Haemangioendothelioma in a preterm infant associated with highly elevated alpha-fetoprotein.European journal of pediatrics · 1996Article
- renal tumors and tumor-like lesions in pediatric patients.Pediatric nephrology (Berlin, Germany) · 1992Review
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
We examined 226 abdominal, retroperitoneal and sacrococcygeal tumours in newborns and infants aged 6 months or less. Most frequent were neuroblastomas (n = 83) followed by germ cell tumours (n = 76), 37 of which were immature and 32 were mature teratomas. Fully malignant germ cell tumours and malignant germ cell tumour components were much rarer in this age group (9.2%) than in older children (58.1%). The majority of germ cell tumours were localized in the sacrococcygeal region (72.4%). Next in frequency were tumours of the kidney (n = 54), including 28 congenital mesoblastic nephromas. In contrast to children over 6 months of age, kidney tumours were frequently low grade malignant with a favourable prognosis. Among liver tumours there were 19 infantile haemangioendotheliomas and 9 hepatoblastomas. By contrast, at ages 7-24 months hepatoblastomas (n = 28) were much more frequent than haemangioendotheliomas (n = 2). Tumours in the newborn and very young infant differ from those in older children in many respects: (1) the relative frequency; (2) localization; (3) distribution of histological types; (4) degree of differentiation, often associated with a tendency toward maturation but occasionally also with increasing malignancy; and (5) prognosis, which is comparatively favourable.
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