Evidence map›Paper›PMID 25516870›Full record

ArticleWorld journal of clinical cases2014

Relapsing polychondritis with p-ANCA associated vasculitis: Which triggers the other?

Ibolya File, Csilla Trinn, Zsolt Mátyus, László Ujhelyi, József Balla, János Mátyus

Open access · hybridAbstract readCase Reports
In one paragraph

Article in World journal of clinical cases, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Observational
  4. Article
  5. Review
  6. Refractory relapsing polychondritis: challenges and solutions.Open access rheumatology : research and reviews · 2018
    Review
  7. Connective Tissue Disorder-Associated Vasculitis.Current rheumatology reports · 2016
    Review
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ibolya FileIbolya File, Csilla Trinn, László Ujhelyi, József Balla, János Mátyus, Institute of Internal Medicine, University of Debrecen, Clinical Centre, H-4032 Debrecen, Hungary.
Csilla TrinnIbolya File, Csilla Trinn, László Ujhelyi, József Balla, János Mátyus, Institute of Internal Medicine, University of Debrecen, Clinical Centre, H-4032 Debrecen, Hungary.
Zsolt MátyusIbolya File, Csilla Trinn, László Ujhelyi, József Balla, János Mátyus, Institute of Internal Medicine, University of Debrecen, Clinical Centre, H-4032 Debrecen, Hungary.
László UjhelyiIbolya File, Csilla Trinn, László Ujhelyi, József Balla, János Mátyus, Institute of Internal Medicine, University of Debrecen, Clinical Centre, H-4032 Debrecen, Hungary.
József BallaIbolya File, Csilla Trinn, László Ujhelyi, József Balla, János Mátyus, Institute of Internal Medicine, University of Debrecen, Clinical Centre, H-4032 Debrecen, Hungary.
János MátyusIbolya File, Csilla Trinn, László Ujhelyi, József Balla, János Mátyus, Institute of Internal Medicine, University of Debrecen, Clinical Centre, H-4032 Debrecen, Hungary.
University of Debrecen · HU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Relapsing polychondritis (RP) is a rare autoimmune disease with chronic inflammatory/destructive lesions of the cartilaginous tissues. In one third of the cases it is associated with other autoimmune disorders, mostly with anti-neutrophil cytoplasmic antibody (ANCA) associated vasculitis (AAV). We report three cases of RP with p-ANCA positive AAV. In the first patient RP developed 1.5 years after the onset of AAV. In the others the signs of RP were present before the onset of severe crescent glomerulonephritis. Patients responded well on steroid and cyclophosphamide. In dialysis dependent cases plasmapheresis was also used successfully. During the 2 and 1.5 years of follow up, they were symptom-free, and had stable glomerular filtration rate. The first patient died after four years of follow-up due to the complications of sudden unset pancytopenia, which raises the possibility of associated hemophagocytic syndrome. In the setting of RP or AAV physicians should always be aware of the possibility of sudden or insidious appearance of the other disease.

Indexed as

Anti-neutrophil cytoplasmic antibodyAnti-neutrophil cytoplasmic antibody-associated vasculitisImmunosuppressive treatmentRapidly progressive glomerulonephritisRelapsing polychondritis

Identifiers

PMID25516870
PMCPMC4266843
OpenAlexW2085804141

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.