Evidence map›Paper›PMID 25516831›Full record

ArticleInternational journal for parasitology. Drugs and drug resistance2014

Anthelmintics - from discovery to resistance.

Adrian J Wolstenholme, Richard J Martin

Abstract read
In one paragraph

Article in International journal for parasitology. Drugs and drug resistance, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Essential Oils as Novel Anthelmintic Drug Candidates.Molecules (Basel, Switzerland) · 2022
    Review
  2. Article
  3. Genetic Markers of Benzimidazole Resistance among Human Hookworms (The American journal of tropical medicine and hygiene · 2019
    Article
  4. Anthelmintics - From Discovery to Resistance III (Indian Rocks Beach, FL, 2018).International journal for parasitology. Drugs and drug resistance · 2018
    Article
  5. Article
  6. Review
  7. Article
  8. Article
  9. Anthelmintics: From discovery to resistance II (San Diego, 2016).International journal for parasitology. Drugs and drug resistance · 2016
    Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Adrian J WolstenholmeDepartment of Infectious Diseases, University of Georgia, Athens, GA 30602, USA ; Center for Tropical and Emerging Global Diseases, University of Georgia, Athens, GA 30602, USA.
Richard J MartinDepartment of Biomedical Sciences, Iowa State University, Ames, IA 50011, USA.

Funding

RESISTANCE &MODULATION OF LEVAMISOLE RECEPTOR CHANNELSR01AI047194 · NIAID · IOWA STATE UNIVERSITY · PI MARTIN, RICHARD JOHN · 2001 to 2021
$5.8M
Anthelmintics: From discovery of new drugs to modes of action and resistanceR13AI109813 · NIAID · UNIVERSITY OF GEORGIA · PI WOLSTENHOLME, ADRIAN J · 2014 to 2014
$5k
NIAID NIH HHS R01 AI047194NIAID NIH HHS R13 AI109813
6 · The paper itself

Abstract

The scientific meeting entitled 'Anthelmintics: From Discovery to Resistance' was held in San Francisco in February 2014. The themes of the meeting were drug discovery, modes of action and resistance. Both human and veterinary parasites were covered in the oral and poster presentations. The attendees were from both academic and industrial backgrounds. In the present article we introduce a number of the papers that emerged from the meeting. Several of the papers covered current drug discovery efforts underway worldwide, with some specific examples focusing on ion channels, protein kinases and cysteine proteases. These efforts included the repurposing of known drugs as well as the discovery of novel actives. Two papers described recently-developed whole-organism screening techniques. Finally, we introduce several papers looking at mechanisms and management of drug resistance in human and veterinary parasites.

Indexed as

AnthelminticsDrug discoveryResistanceScientific meeting

Identifiers

PMID25516831
PMCPMC4266783

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.