Evidence map›Paper›PMID 25516714›Full record

ReviewInternational journal of biological sciences2014

Flavonoids and Melanins: a common strategy across two kingdoms.

Giorgia Carletti, Giuseppe Nervo, Luigi Cattivelli

Open access · goldAbstract readReview
In one paragraph

Review in International journal of biological sciences, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
7.0field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 91 citations in OpenAlex.

  1. Article
  2. Metal Ion Supplementation to Boost Melanin Production byInternational journal of molecular sciences · 2025
    Article
  3. Article
  4. Article
  5. A Phytobiotic Supersupplement FromAquaculture nutrition · 2025
    Article
  6. Review
  7. Article
  8. Article
  9. Pigments from pathogenic bacteria: a comprehensive update on recent advances.World journal of microbiology & biotechnology · 2024
    Review
  10. Article
  11. FermentedMolecules (Basel, Switzerland) · 2023
    Article
  12. Article
  13. Journal of biomolecular structure & dynamics · 2022
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Giorgia Carletti1. Consiglio per la Ricerca e la Sperimentazione in Agricoltura, Research Unit for Intensive Wood Production, Strada Frassineto 35, 15033 Casale Monferrato, AL, Italy;
Giuseppe Nervo1. Consiglio per la Ricerca e la Sperimentazione in Agricoltura, Research Unit for Intensive Wood Production, Strada Frassineto 35, 15033 Casale Monferrato, AL, Italy;
Luigi Cattivelli2. Consiglio per la Ricerca e la Sperimentazione in Agricoltura, Genomics Research Centre, via S Protaso 302, I-29107 Fiorenzuola d'Arda, PC, Italy.
Istituto Sperimentale per la Frutticoltura · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ultraviolet (UV) radiations alter a number of metabolic functions in vivant. They produce damages to lipids, nucleic acids and proteins, generating reactive oxygen species such as singlet oxygen (O2), hydroxyl radical (HO) and superoxide anion (O2 (-)). Plants and animals, after their water emersion, have developed biochemical mechanisms to protect themselves from that environmental threat through a common strategy. Melanins in animals and flavonoids in plants are antioxidant pigments acting as free radical scavenging mechanisms. Both are phenol compounds constitutively synthesized and enhanced after exposure to UV rays, often conferring a red-brown-dark tissue pigmentation. Noteworthy, beside anti-oxidant scavenging activity, melanins and flavonoids have acquired secondary functions that, both in plants and animals, concern reproductions and fitness. Plants highly pigmented are more resistant to biotic and abiotic stresses. Darker wild vertebrates are generally more aggressive, sexually active and resistant to stress than lighter individuals. Flavonoids have been associated with signal attraction between flowers and insects and with plant-plant interaction. Melanin pigmentation has been proposed as trait in bird communication, acting as honest signals of quality. This review shows how the molecular mechanisms leading to tissue pigmentation have many functional analogies between plants and animals and how their origin lies in simpler organisms such as Cyanobacteria. Comparative studies between plant and animal kingdoms can reveal new insight of the antioxidant strategies in vivant.

Indexed as

Biological EvolutionAnimalsAntioxidantsBetalainsFlavonoidsFree Radical ScavengersGenetic FitnessMelaninsMetabolic Networks and PathwaysMolecular StructurePigmentationPlantsReproductionUltraviolet RaysAntioxidantsBetalainsFlavonoidsFree Radical ScavengersMelaninsantioxidant strategy, pigments, horizontal gene transfer (HGT)plants, animals, metabolism, genetic bases, mutants.

Identifiers

PMID25516714
PMCPMC4261200
OpenAlexW2116878325

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.