Evidence map›Paper›PMID 25516708›Full record

SynthesisJSLS : Journal of the Society of Laparoendoscopic Surgeons

Meta-analysis of drainage versus no drainage after laparoscopic cholecystectomy.

Marcello Picchio, Pierino Lucarelli, Annalisa Di Filippo, Francesco De Angelis, Francesco Stipa, Erasmo Spaziani

Open access · hybridAbstract readMeta-AnalysisReview
In one paragraph

Synthesis in JSLS : Journal of the Society of Laparoendoscopic Surgeons. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Marcello PicchioDepartment of Surgery, Hospital "P. Colombo," Velletri, Italy.
Pierino LucarelliBasildon Hospital, Basildon, England.
Annalisa Di FilippoDepartment of Surgery, University of Rome "La Sapienza," Terracina, Italy.
Francesco De AngelisDepartment of Surgery, University of Rome "La Sapienza," Terracina, Italy.
Francesco StipaDepartment of Surgery, Hospital "S. Giovanni-Addolorata," Rome, Italy.
Erasmo SpazianiDepartment of Surgery, University of Rome "La Sapienza," Terracina, Italy.
Basildon Hospital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

objectivesRoutine drainage after laparoscopic cholecystectomy is still controversial. This meta-analysis was performed to assess the role of drains in reducing complications in laparoscopic cholecystectomy.

methodsAn electronic search of Medline, Science Citation Index Expanded, Scopus, and the Cochrane Library database from January 1990 to June 2013 was performed to identify randomized clinical trials that compare prophylactic drainage with no drainage in laparoscopic cholecystectomy. The odds ratio for qualitative variables and standardized mean difference for continuous variables were calculated.

resultsTwelve randomized controlled trials were included in the meta-analysis, involving 1939 patients randomized to a drain (960) versus no drain (979). The morbidity rate was lower in the no drain group (odds ratio, 1.97; 95% confidence interval, 1.26 to 3.10; P = .003). The wound infection rate was lower in the no drain group (odds ratio, 2.35; 95% confidence interval, 1.22 to 4.51; P = .01). Abdominal pain 24 hours after surgery was less severe in the no drain group (standardized mean difference, 2.30; 95% confidence interval, 1.27 to 3.34; P < .0001). No significant difference was present with respect to the presence and quantity of subhepatic fluid collection, shoulder tip pain, parenteral ketorolac consumption, nausea, vomiting, and hospital stay.

conclusionThis study was unable to prove that drains were useful in reducing complications in laparoscopic cholecystectomy.

Indexed as

Cholecystectomy, LaparoscopicDrainageHumansPostoperative CarePostoperative ComplicationsCholecystectomyDrainageLaparoscopy

Identifiers

PMID25516708
PMCPMC4266231
OpenAlexW2329140131

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.