Evidence map›Paper›PMID 25516679›Full record

SynthesisWorld journal of gastroenterology2014

Helicobacter pylori infection and atopic diseases: is there a relationship? A systematic review and meta-analysis.

Elena Lionetti, Salvatore Leonardi, Angela Lanzafame, Maria Teresa Garozzo, Martina Filippelli, Stefania Tomarchio, Viviana Ferrara, Carmelo Salpietro, Alfredo Pulvirenti, Ruggiero Francavilla and 1 more

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. The updated JSPGHAN guidelines for the management of Helicobacter pylori infection in childhood.Pediatrics international : official journal of the Japan Pediatric Society · 2020
    Guideline
  2. Update on the association between Helicobacter pylori infection and asthma in terms of microbiota and immunity.Allergy, asthma, and clinical immunology : official journal of the Canadian Society of Allergy and Clinical Immunology · 2024
    Review
  3. Therapeutic advances in gastroenterology · 2023
    Review
  4. Journal of clinical medicine · 2022
    Review
  5. Article
  6. Helicobacter pylori Infection: New Facts in Clinical Management.Current treatment options in gastroenterology · 2018
    Review
  7. Pediatric gastroenterology, hepatology & nutrition · 2017
    Article
  8. The landscape of genetic susceptibility correlations among diseases and traits.Journal of the American Medical Informatics Association : JAMIA · 2017
    Article
  9. Population screening and treatment of Helicobacter pylori infection.Nature reviews. Gastroenterology & hepatology · 2017
    Review
  10. Frontiers in cellular and infection microbiology · 2017
    Article
  11. Frontiers in microbiology · 2017
    Review
  12. Therapeutics and clinical risk management · 2017
    Article
  13. Association Between Helicobacter pylori Infection and Risk of Periodontal Diseases in Han Chinese: A Case-Control Study.Medical science monitor : international medical journal of experimental and clinical research · 2016
    Article
  14. Helicobacter pylori and allergy: Update of research.World journal of methodology · 2015
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Elena LionettiElena Lionetti, Salvatore Leonardi, Angela Lanzafame, Maria Teresa Garozzo, Martina Filippelli, Stefania Tomarchio, Viviana Ferrara, Department of Pediatrics, University of Catania, 95100 Catania, Italy.
Salvatore LeonardiElena Lionetti, Salvatore Leonardi, Angela Lanzafame, Maria Teresa Garozzo, Martina Filippelli, Stefania Tomarchio, Viviana Ferrara, Department of Pediatrics, University of Catania, 95100 Catania, Italy.
Angela LanzafameElena Lionetti, Salvatore Leonardi, Angela Lanzafame, Maria Teresa Garozzo, Martina Filippelli, Stefania Tomarchio, Viviana Ferrara, Department of Pediatrics, University of Catania, 95100 Catania, Italy.
Maria Teresa GarozzoElena Lionetti, Salvatore Leonardi, Angela Lanzafame, Maria Teresa Garozzo, Martina Filippelli, Stefania Tomarchio, Viviana Ferrara, Department of Pediatrics, University of Catania, 95100 Catania, Italy.
Martina FilippelliElena Lionetti, Salvatore Leonardi, Angela Lanzafame, Maria Teresa Garozzo, Martina Filippelli, Stefania Tomarchio, Viviana Ferrara, Department of Pediatrics, University of Catania, 95100 Catania, Italy.
Stefania TomarchioElena Lionetti, Salvatore Leonardi, Angela Lanzafame, Maria Teresa Garozzo, Martina Filippelli, Stefania Tomarchio, Viviana Ferrara, Department of Pediatrics, University of Catania, 95100 Catania, Italy.
Viviana FerraraElena Lionetti, Salvatore Leonardi, Angela Lanzafame, Maria Teresa Garozzo, Martina Filippelli, Stefania Tomarchio, Viviana Ferrara, Department of Pediatrics, University of Catania, 95100 Catania, Italy.
Carmelo SalpietroElena Lionetti, Salvatore Leonardi, Angela Lanzafame, Maria Teresa Garozzo, Martina Filippelli, Stefania Tomarchio, Viviana Ferrara, Department of Pediatrics, University of Catania, 95100 Catania, Italy.
Alfredo PulvirentiElena Lionetti, Salvatore Leonardi, Angela Lanzafame, Maria Teresa Garozzo, Martina Filippelli, Stefania Tomarchio, Viviana Ferrara, Department of Pediatrics, University of Catania, 95100 Catania, Italy.
Ruggiero FrancavillaElena Lionetti, Salvatore Leonardi, Angela Lanzafame, Maria Teresa Garozzo, Martina Filippelli, Stefania Tomarchio, Viviana Ferrara, Department of Pediatrics, University of Catania, 95100 Catania, Italy.
Carlo CatassiElena Lionetti, Salvatore Leonardi, Angela Lanzafame, Maria Teresa Garozzo, Martina Filippelli, Stefania Tomarchio, Viviana Ferrara, Department of Pediatrics, University of Catania, 95100 Catania, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo review and conduct a meta-analysis of the existing literature on the relationship between Helicobacter pylori (H. pylori), atopy and allergic diseases.

methodsStudies published in English assessing the prevalence of atopy and/or allergic diseases in patients with H. pylori infection and the prevalence of H. pylori infection in patients with atopy and/or allergic diseases were identified through a MEDLINE search (1950-2014). Random-effect model was used for the meta-analysis.

resultsPooled results of case-control studies showed a significant inverse association of H. pylori infection with atopy/allergic disease or with exclusively atopy, but not with allergic disease, whereas pooled results of cross-sectional studies showed only a significant association between allergic disease and H. pylori infection.

conclusionThere is some evidence of an inverse association between atopy/allergic diseases and H. pylori infection, although further studied are needed.

Indexed as

Helicobacter InfectionsHelicobacter pyloriHumansHypersensitivityOdds RatioPrognosisRisk AssessmentRisk FactorsAllergic diseasesAtopyHelicobacter pyloriHygiene hypothesisInfection

Identifiers

PMID25516679
PMCPMC4265626

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.