Evidence map›Paper›PMID 25516667›Full record

ArticleWorld journal of gastroenterology2014

Clinical epidemiology of ulcerative colitis in Arabs based on the Montréal classification.

Othman R Alharbi, Nahla A Azzam, Ahmed S Almalki, Majid A Almadi, Khalid A Alswat, Nazia Sadaf, Abdulrahman M Aljebreen

Open access · hybridAbstract read
In one paragraph

Article in World journal of gastroenterology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it, 35 citations in OpenAlex.

  1. Pooled it
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  7. Saudi consensus guidance for the management of inflammatory bowel disease during pregnancy.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Othman R AlharbiOthman R Alharbi, Nahla A Azzam, Majid A Almadi, Khalid A Alswat, Nazia Sadaf, Abdulrahman M Aljebreen, Gastroenterology Division, King Khalid University Hospital, King Saud University, Riyadh 11461, Saudi Arabia.
Nahla A AzzamOthman R Alharbi, Nahla A Azzam, Majid A Almadi, Khalid A Alswat, Nazia Sadaf, Abdulrahman M Aljebreen, Gastroenterology Division, King Khalid University Hospital, King Saud University, Riyadh 11461, Saudi Arabia.
Ahmed S AlmalkiOthman R Alharbi, Nahla A Azzam, Majid A Almadi, Khalid A Alswat, Nazia Sadaf, Abdulrahman M Aljebreen, Gastroenterology Division, King Khalid University Hospital, King Saud University, Riyadh 11461, Saudi Arabia.
Majid A AlmadiOthman R Alharbi, Nahla A Azzam, Majid A Almadi, Khalid A Alswat, Nazia Sadaf, Abdulrahman M Aljebreen, Gastroenterology Division, King Khalid University Hospital, King Saud University, Riyadh 11461, Saudi Arabia.
Khalid A AlswatOthman R Alharbi, Nahla A Azzam, Majid A Almadi, Khalid A Alswat, Nazia Sadaf, Abdulrahman M Aljebreen, Gastroenterology Division, King Khalid University Hospital, King Saud University, Riyadh 11461, Saudi Arabia.
Nazia SadafOthman R Alharbi, Nahla A Azzam, Majid A Almadi, Khalid A Alswat, Nazia Sadaf, Abdulrahman M Aljebreen, Gastroenterology Division, King Khalid University Hospital, King Saud University, Riyadh 11461, Saudi Arabia.
Abdulrahman M AljebreenOthman R Alharbi, Nahla A Azzam, Majid A Almadi, Khalid A Alswat, Nazia Sadaf, Abdulrahman M Aljebreen, Gastroenterology Division, King Khalid University Hospital, King Saud University, Riyadh 11461, Saudi Arabia.
King Khalid University Hospital · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimTo determine the clinical, epidemiological and phenotypic characteristics of ulcerative colitis (UC) in Saudi Arabia by studying the largest cohort of Arab UC patients.

methodsData from UC patients attending gastroenterology clinics in four tertiary care centers in three cities between September 2009 and September 2013 were entered into a validated web-based registry, inflammatory bowel disease information system (IBDIS). The IBDIS database covers numerous aspects of inflammatory bowel disease. Patient characteristics, disease phenotype and behavior, age at diagnosis, course of the disease, and extraintestinal manifestations were recorded.

resultsAmong 394 UC patients, males comprised 51.0% and females 49.0%. According to the Montréal classification of age, the major chunk of our patients belonged to the A2 category for age of diagnosis at 17-40 years (68.4%), while 24.2% belonged to the A3 category for age of diagnosis at > 40 years. According to the same classification, a majority of patients had extensive UC (42.7%), 35.3% had left-sided colitis and 29.2% had only proctitis. Moreover, 51.3% were in remission, 16.6% had mild UC, 23.4% had moderate UC and 8.6% had severe UC. Frequent relapse occurred in 17.4% patients, infrequent relapse in 77% and 4.8% had chronic disease. A majority (85.2%) of patients was steroid responsive. With regard to extraintestinal manifestations, arthritis was present in 16.4%, osteopenia in 31.4%, osteoporosis in 17.1% and cutaneous involvement in 7.0%.

conclusionThe majority of UC cases were young people (17-40 years), with a male preponderance. While the disease course was found to be similar to that reported in Western countries, more similarities were found with Asian countries with regards to the extent of the disease and response to steroid therapy.

Indexed as

ArabsAdolescentAdultAge FactorsColitis, UlcerativeCross-Sectional StudiesFemaleHumansMalePhenotypePrevalenceProspective StudiesRecurrenceRegistriesRemission InductionRisk FactorsSteroidsEpidemiologyInflammatory bowel disease information systemSaudi ArabiaUlcerative colitis

Identifiers

PMID25516667
PMCPMC4265614
OpenAlexW2003005200

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.