Evidence map›Paper›PMID 25516223›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2015

Efficacy of sublingual immunotherapy for house dust mite allergic rhinitis.

Cemal Cingi, Nuray Bayar Muluk, Seçkin Ulusoy, Mustafa Acar, Seher Şirin, Bengü Çobanoğlu, Leman Birdane, Çiğdem Kalaycık, Burak Ömür Çakır, Fatih Oğhan and 8 more

Abstract readMulticenter Study
PubMed Publisher
In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. A Survey of Korean Physicians' Prescription Patterns for Allergic Rhinitis.Clinical and experimental otorhinolaryngology · 2017
    Article
  5. Article
  6. The Future of Sublingual Immunotherapy in the United States.Current allergy and asthma reports · 2015
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 9 institutions in 1 country.

Cemal CingiENT Department, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey.
Nuray Bayar MulukENT Department, Medical Faculty, Kırıkkale University, Kırıkkale, Turkey. nbayarmuluk@yahoo.com.
Seçkin UlusoyENT Clinics, Gaziosmanpaşa Taksim Ilkyardım Training and Research Hospital, TR Ministry of Health, Istanbul, Turkey.
Mustafa AcarENT Clinics, Yunus Emre State Hospital, TR Ministry of Health, Eskisehir, Turkey.
Seher ŞirinENT Clinics, Derince Training and Research Hospital, TR Ministry of Health, Derince, Turkey.
Bengü ÇobanoğluENT Clinics, Trabzon Training and Research Hospital, TR Ministry of Health, Trabzon, Turkey.
Leman BirdaneENT Clinics, Yunus Emre State Hospital, TR Ministry of Health, Eskisehir, Turkey.
Çiğdem KalaycıkENT Department, Medical Faculty, Başkent University, Istanbul, Turkey.
Burak Ömür ÇakırAnatomica Ear Nose Throat Clinic, Istanbul, Turkey.
Fatih OğhanENT Department, Medical Faculty, Kütahya Dumlupınar University, Kütahya, Turkey.
Sevilay AynacıENT Clinics, Eskişehir State Hospital, TR Ministry of Health, Eskisehir, Turkey.
Nagehan ErdoğmuşENT Clinics, Osmaniye State Hospital, TR Ministry of Health, Osmaniye, Turkey.
Ömürsen YıldırımENT Clinics, Iğdır State Hospital, TR Ministry of Health, Iğdır, Turkey.
Ethem ŞahinENT Clinics, Bayındır İstanbul Hospital, Istanbul, Turkey.
Fuat BulutENT Clinics, Diyarbakır Memorial Hospital, Diyarbakır, Turkey.
Mehmet Akif AksoyENT Department, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey.
Nurullah TüreENT Department, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey.
Cengiz BalBiostatistics Department, Medical Faculty, Eskisehir Osmangazi University, Eskisehir, Turkey.
Ministry of Health · TREskişehir Osmangazi University · TRBaşkent University · TRBayındır Hastanesi · TRDiyarbakır Askeri Hastanesi · TRDumlupinar University · TRGaziosmanpaşa Taksim Eğitim ve Araştırma Hastanesi · TRKırıkkale University · TRTurkish Society of Hematology · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In the present study, we investigated the outcomes of sublingual immunotherapy (SLIT) in house dust mite-induced allergic rhinitis (HDM-AR) patients. In this prospective, multicentric study, 186 patients with AR who had positive skin prick test results for HDMs were included. The patients were administered SLIT using Staloral 300 for 1 year. Evaluation of the patients regarding symptom scores, clinical findings and Rhinitis Quality of Life Questionnaire (RQLQ) scores was performed at baseline, and then at 6 and 12 months of therapy. Our results showed that, for all of the evaluated items (symptom scores, clinical findings and RQLQ scores), 12-month values were significantly lower than those at 6 months and baseline. Similarly, 6-month values were significantly lower than those at baseline. There were no complications in any of our patients. SLIT for HDM-AR is a treatment modality that can be used safely. We obtained better results than expected, and the treatment showed a positive psychological effect; the patients believed that SLIT was the final step of treatment and, which made them feel better.

Indexed as

Sublingual ImmunotherapyAdultAnimalsAntigens, DermatophagoidesFemaleHumansMaleMiddle AgedProspective StudiesPyroglyphidaeQuality of LifeRhinitis, Allergic, PerennialSurveys and QuestionnairesTreatment OutcomeYoung AdultAntigens, DermatophagoidesAllergic rhinitis (AR)House dust mite (HDM)Rhinitis Quality of Life Questionnaire (RQLQ)Sublingual immunotherapy (SLIT)

Identifiers

PMID25516223
OpenAlexW2071762345

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.