Evidence map›Paper›PMID 25516068›Full record

ArticleAlcoholism, clinical and experimental research2015

Latent trajectory classes for alcohol-related blackouts from age 15 to 19 in ALSPAC.

Marc A Schuckit, Tom L Smith, Jon Heron, Matthew Hickman, John Macleod, Marcus R Munafo, Kenneth S Kendler, Danielle M Dick, George Davey-Smith

Open access · greenAbstract read
In one paragraph

Article in Alcoholism, clinical and experimental research, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

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  15. Intentions and motives to experience alcohol-induced blackout among young adults in college.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Marc A SchuckitDepartment of Psychiatry, University of California, San Diego, La Jolla, California.
Tom L Smith
Jon Heron
Matthew Hickman
John Macleod
Marcus R Munafo
Kenneth S Kendler
Danielle M Dick
George Davey-Smith
University of Bristol · GBUniversity of California, San Diego · USVirginia Commonwealth University · US

Funding

REACTIONS TO DEPRESSANTS IN SONS OF ALCSR01AA005526 · NIAAA · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI SCHUCKIT, MARC A · 1986 to 2010
$4.1M
Pathways to Alcohol Use Disorders in ALSPAC: A Genetic-Developmental StudyR01AA018333 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI DICK, DANIELLE M, KENDLER, KENNETH SEEDMAN · 2010 to 2014
$2.8M
Twin, molecular, and developmental approaches to understanding alcohol misuseK02AA018755 · NIAAA · VIRGINIA COMMONWEALTH UNIVERSITY · PI DICK, DANIELLE M · 2010 to 2019
$1.3M
PREVENTION APPROACH TO COLLEGE HEAVY DRINKING BASED ON A LOW RESPONSE TO ALCOHOLR01AA021162 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SCHUCKIT, MARC A · 2013 to 2014
$945k
Using Placebo and Alcohol Session fMRI to Predict Adverse Alcohol OutcomesR21AA021827 · NIAAA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI SCHUCKIT, MARC A · 2013 to 2014
$398k
Medical Research Council G0800612Medical Research Council G0802736Medical Research Council MC_PC_15018Medical Research Council MC_UU_12013/1Medical Research Council MC_UU_12013/6Medical Research Council MR/K023195/1Medical Research Council MR/K023233/1NIAAA NIH HHS K02 AA018755NIAAA NIH HHS R01 AA005526NIAAA NIH HHS R01 AA018333NIAAA NIH HHS R01 AA021162NIAAA NIH HHS R21 AA021827Wellcome Trust 102215
6 · The paper itself

Abstract

backgroundAlcohol-related blackouts (ARBs) are reported by ~50% of drinkers. While much is known about the prevalence of ARBs in young adults and their cross-sectional correlates, there are few prospective studies regarding their trajectories over time during mid-adolescence. This paper reports latent trajectory classes of ARBs between age 15 and 19, along with predictors of those patterns.

methodsLatent class growth analysis (LCGA) was used to evaluate the pattern of occurrence of ARBs across 4 time points for 1,402 drinking adolescents from the Avon Longitudinal Study of Parents and Children (ALSPAC). Multinomial regression analyses evaluated age-15 demography, substance-related items, externalizing characteristics, and estimated peer substance use as predictors of latent class membership.

resultsARBs were reported at age 15 in 30% and at age 19 in 74% of these subjects. Four latent trajectory classes were identified: Class 1 (5.1%) reported no blackouts; for Class 2 (29.5%), ARBs rapidly increased with age; for Class 3 (44.9%), blackouts slowly increased; and for Class 4 (20.5%), ARBs were consistently reported. Using Class 2 (rapid increasers) as the reference, predictors of class membership included female sex, higher drinking quantities, smoking, externalizing characteristics, and estimated peer substance involvement (pseudo R(2)  = 0.22).

conclusionsARBs were common and repetitive in these young subjects, and predictors of their trajectories over time involved multiple domains representing diverse characteristics.

Indexed as

AdolescentAge FactorsAmnesiaEnglandEthanolFemaleHumansMaleModels, PsychologicalProspective StudiesRisk FactorsSex FactorsYoung AdultEthanolAlcoholBlackoutsLatent TrajectoriesPredictors

Identifiers

PMID25516068
PMCPMC4308468
OpenAlexW2026846340

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.