Evidence map›Paper›PMID 25516025›Full record

Trial reportJournal of the American Geriatrics Society2014

Cost-effectiveness of a community-integrated home-based depression intervention in older African Americans.

Laura T Pizzi, Eric Jutkowitz, Kevin D Frick, Dong-Churl Suh, Katherine M Prioli, Laura N Gitlin

Registry-linked trialOpen access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Geriatrics Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03239665 (Randomized Trial of Peer-to-Peer Versus Pharmacist Education to Improve Older Adults' Vaccination Knowledge Through the Senior Center Model of Care), which is not on this map. Cited by 10 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 3 pooled it
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03239665 nacompletednot on this mapstarted 2017, after this paper: background citation

Randomized Trial of Peer-to-Peer Versus Pharmacist Education to Improve Older Adults' Vaccination Knowledge Through the Senior Center Model of Care

TypeinterventionalSponsorRutgers, The State University of New JerseyRan2017 to 2019Enrolled335ConditionsInfectious Disease, Pneumonia, Bacterial, Influenza, ZosterArmsPharmacist-led Intervention (PHARM), Peer-led Intervention (PEER)
3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 3 syntheses or guidelines pooled it, 18 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 2 countries.

Laura T PizziJefferson School of Pharmacy, Thomas Jefferson University, Philadelphia, Pennsylvania.
Eric Jutkowitz
Kevin D Frick
Dong-Churl Suh
Katherine M Prioli
Laura N Gitlin
Johns Hopkins University · USThomas Jefferson University · USChung-Ang University · KRUniversity of Minnesota · US

Funding

Treating Depression in African American Elders: A Community-Academic PartnershipR01MH079814 · NIMH · THOMAS JEFFERSON UNIVERSITY · PI GITLIN, LAURA N. · 2007 to 2011
$2.9M
Cost Effectiveness of a Home Support Program for Depression in Black EldersRC1MH090770 · NIMH · THOMAS JEFFERSON UNIVERSITY · PI GITLIN, LAURA N. · 2009 to 2010
$997k
NIMH NIH HHS R01 MH 079814NIMH NIH HHS R01 MH079814NIMH NIH HHS RC1MH09077NIMH NIH HHS RC1 MH090770
6 · The paper itself

Abstract

objectivesTo test the cost-effectiveness of a home-based depression program: Beat the Blues (BTB).

designA cost-effectiveness analysis as part of a previously reported randomized controlled trial that compared BTB with a wait-list control group.

settingCommunity.

participantsEnglish-speaking, cognitively intact (Mini-Mental State Examination score ≥24), African Americans aged 55 and older with depressive symptoms (Patient Health Questionnaire score ≥5) (N = 129).

interventionParticipants randomly assigned to BTB received up to 10 home visits over 4 months from licensed social workers who provided care management, referral and linkage, stress reduction, depression education, and behavioral activation to help participants achieve self-identified goals. MEASUREMENTS: Incremental cost-effectiveness ratios (ICERs) of BTB versus wait-list controls during the 4-month study period. The primary ICER was defined as cost per quality-adjusted life year (QALY) using the Euro Quality of Life 5D (EQ-5D) and secondarily using the Health Utilities Index-3 (HUI-3). Additional ICERs were calculated using clinical measures (cost per depression improvement, cost per depression remission). Costs included BTB intervention, depression-related healthcare visits and medications, caregiver time, and social services.

resultsBTB cost per participant per month was $146. Base case ICERs were $64,896 per QALY (EQ-5D) and $36,875 per QALY (HUI-3). Incremental cost was $2,906 per depression improvement and $3,507 per remission. Univariate and probabilistic sensitivity analyses yielded a cost/QALY range of $20,500 to $76,500.

conclusionBased on the range of cost-effectiveness values resulting from this study, BTB is a cost-effective treatment for managing depressive symptoms in older African Americans that compares favorably with the cost-effectiveness of previously tested approaches.

Indexed as

Activities of Daily LivingAgedAged, 80 and overBlack or African AmericanComorbidityCost-Benefit AnalysisDemographyDepressionFemaleHome Care ServicesHumansMaleQuality-Adjusted Life YearsSurveys and QuestionnairesTreatment OutcomeAfrican Americancostcost-effectivenessdepressionhealth utility

Identifiers

PMID25516025
PMCPMC4270093
OpenAlexW2084846736

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.