Evidence map›Paper›PMID 25516024›Full record

Trial reportJournal of the American Geriatrics Society2014

Factors mediating the effects of a depression intervention on functional disability in older African Americans.

Laura N Gitlin, Sarah L Szanton, Jin Huang, David L Roth

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of the American Geriatrics Society, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Symptomatic and Functional Recovery From Major Depressive Disorder in the Ibadan Study of Ageing.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2018
    Article
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Laura N GitlinCenter for Innovative Care in Aging, Center on Aging and Health, Johns Hopkins University, Baltimore, Maryland.
Sarah L Szanton
Jin Huang
David L Roth
Johns Hopkins University · US

Funding

Treating Depression in African American Elders: A Community-Academic PartnershipR01MH079814 · NIMH · THOMAS JEFFERSON UNIVERSITY · PI GITLIN, LAURA N. · 2007 to 2011
$2.9M
NIMH NIH HHS R01 MH 079814NIMH NIH HHS R01 MH079814
6 · The paper itself

Abstract

objectivesTo determine factors mediating the effects of a depression intervention for older African Americans on functional disability and, secondarily, whether functional improvements mediate intervention effects on depressive symptoms.

designStructural equation modeling to examine mediators in a secondary analysis of a randomized trial with 4-month follow-up.

settingPhiladelphia region.

participantsCommunity-dwelling African Americans (≥55) with depressive symptoms living in an urban area (N = 208).

interventionUp to 10 one-hour sessions over 4 months conducted by licensed social workers who provided care management, referrals and linkages, stress reduction techniques, depression knowledge and symptom recognition, and behavioral activation techniques. MEASUREMENTS: Main outcome was self-reported functional difficulty level for 18 basic activities. Mediators included depression severity (Patient Health Questionnaire), depression knowledge and symptom recognition, behavioral activation, and anxiety.

resultsAt 4 months, the intervention had positive effects on functional difficulty and all mediators (P < .001). Separate structural equation models indicated that two factors (reduced depressive symptoms (23.5% mediated) and improved depression knowledge and symptom recognition (52.9% mediated)) significantly mediated the intervention's effect on functional disability. Enhancing behavioral activation and decreasing anxiety were not found to mediate improvements in functional disability. The two significant mediators jointly explained 62.5% of the intervention's total effect on functional disability. Functional improvement was not found to mediate the intervention's effect on depressive symptoms.

conclusionThis multicomponent depression intervention for African Americans has an effect on functional disability that is driven primarily by enhancing symptom recognition and decreasing depressive symptoms. Reduction of functional difficulties did not account for improvements in depressive symptoms. Nonpharmacological treatments for depressive symptoms that enhance symptom recognition in older African Americans can also reduce their functional difficulties with daily living activities.

Indexed as

Activities of Daily LivingAgedAged, 80 and overBlack or African AmericanDepressionFemaleFollow-Up StudiesHumansMaleMiddle AgedPennsylvaniaPersons with DisabilitiesSurveys and QuestionnairesTreatment Outcomedepressionfunctional disabilitymediation analysis

Identifiers

PMID25516024
PMCPMC4415989
OpenAlexW2035800179

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.