Evidence map›Paper›PMID 25515717›Full record

ArticleJournal of oncology practice2015

Population-based assessment of cancer survivors' financial burden and quality of life: a prospective cohort study.

S Yousuf Zafar, Rebecca B McNeil, Catherine M Thomas, Christopher S Lathan, John Z Ayanian, Dawn Provenzale

Abstract read
In one paragraph

Article in Journal of oncology practice, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 196 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
196citing papers in PubMed, 7 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

196 citing papers in PubMed, 7 syntheses or guidelines pooled it.

  1. Measures of financial toxicity in cancer survivors: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  2. Pooled it
  3. Guideline
  4. Pooled it
  5. Financial Burdens of Cancer Treatment: A Systematic Review of Risk Factors and Outcomes.Journal of the National Comprehensive Cancer Network : JNCCN · 2019
    Pooled it
  6. Methods for measuring financial toxicity after cancer diagnosis and treatment: a systematic review and its implications.Annals of oncology : official journal of the European Society for Medical Oncology · 2019
    Pooled it
  7. Pooled it
  8. Financial hardship experience in middle- and older-aged patients with advanced lung cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Trial
  9. Trial
  10. A proactive financial navigation intervention in patients with newly diagnosed gastric and gastroesophageal junction adenocarcinoma.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Trial
  11. Financial Toxicity Monitoring in a Randomized Controlled Trial of Patient-Reported Outcomes During Cancer Treatment (Alliance AFT-39).Journal of clinical oncology : official journal of the American Society of Clinical Oncology · 2023
    Trial
  12. Trial
  13. Trial
  14. Article
  15. Article
  16. Article
  17. Review
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  19. Article
  20. Article

136 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

S Yousuf ZafarDuke Cancer Institute; Center for Learning Health Care, Duke Clinical Research Institute; Duke University Medical Center; Cooperative Studies Program Epidemiology Center-Durham, Durham Veterans Affairs Medical Center Durham, Durham, NC; Medical University of South Carolina, Charleston, SC; Harvard Medical School; Dana-Farber Cancer Institute; and Brigham and Women's Hospital, Boston, MA yousuf.zafar@duke.edu.
Rebecca B McNeilDuke Cancer Institute; Center for Learning Health Care, Duke Clinical Research Institute; Duke University Medical Center; Cooperative Studies Program Epidemiology Center-Durham, Durham Veterans Affairs Medical Center Durham, Durham, NC; Medical University of South Carolina, Charleston, SC; Harvard Medical School; Dana-Farber Cancer Institute; and Brigham and Women's Hospital, Boston, MA.
Catherine M ThomasDuke Cancer Institute; Center for Learning Health Care, Duke Clinical Research Institute; Duke University Medical Center; Cooperative Studies Program Epidemiology Center-Durham, Durham Veterans Affairs Medical Center Durham, Durham, NC; Medical University of South Carolina, Charleston, SC; Harvard Medical School; Dana-Farber Cancer Institute; and Brigham and Women's Hospital, Boston, MA.
Christopher S LathanDuke Cancer Institute; Center for Learning Health Care, Duke Clinical Research Institute; Duke University Medical Center; Cooperative Studies Program Epidemiology Center-Durham, Durham Veterans Affairs Medical Center Durham, Durham, NC; Medical University of South Carolina, Charleston, SC; Harvard Medical School; Dana-Farber Cancer Institute; and Brigham and Women's Hospital, Boston, MA.
John Z AyanianDuke Cancer Institute; Center for Learning Health Care, Duke Clinical Research Institute; Duke University Medical Center; Cooperative Studies Program Epidemiology Center-Durham, Durham Veterans Affairs Medical Center Durham, Durham, NC; Medical University of South Carolina, Charleston, SC; Harvard Medical School; Dana-Farber Cancer Institute; and Brigham and Women's Hospital, Boston, MA.
Dawn ProvenzaleDuke Cancer Institute; Center for Learning Health Care, Duke Clinical Research Institute; Duke University Medical Center; Cooperative Studies Program Epidemiology Center-Durham, Durham Veterans Affairs Medical Center Durham, Durham, NC; Medical University of South Carolina, Charleston, SC; Harvard Medical School; Dana-Farber Cancer Institute; and Brigham and Women's Hospital, Boston, MA.

Funding

PROPENSITY SCORES IN HIERARCHICAL MODELSU01CA093344 · NCI · DANA-FARBER CANCER INSTITUTE · PI AYANIAN, JOHN Z., FOUAD, MONA N. · 2001 to 2011
$19.5M
Lung/Colon Cancer Outcomes--Cancer Research NetworkU01CA093332 · NCI · DANA-FARBER CANCER INSTITUTE · PI WEEKS, JANE C. · 2001 to 2008
$7.4M
RAND-UCLA CanCORS PDCR ApplicationU01CA093348 · NCI · RAND CORPORATION · PI KAHN, KATHERINE LESLIE · 2001 to 2008
$7.3M
Cancer Care Outcomes Research &Surveillance ConsortiumU01CA093324 · NCI · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI AYANIAN, JOHN Z. · 2001 to 2008
$7.1M
RACIAL DISPARITIES IN END OF LIFE CARE--ACCESSU01CA093329 · NCI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FOUAD, MONA N. · 2001 to 2008
$6.6M
NC Colorectal Cancer Care Outcomes Research StudyU01CA093326 · NCI · UNIV OF NORTH CAROLINA CHAPEL HILL · PI SANDLER, ROBERT S. · 2001 to 2008
$4.3M
Lung Cancer Care Outcomes/Surveillance Consortium-IowaU01CA093339 · NCI · UNIVERSITY OF IOWA · PI WALLACE, ROBERT BRUCE · 2001 to 2008
$3.7M
Inter-disciplinary Program for Training and Mentoring in CER Methods and PracticeKM1CA156687 · NCI · DUKE UNIVERSITY · PI ABERNETHY, AMY P., DELONG, ELIZABETH R. · 2010 to 2010
$2.4M
NCI NIH HHS 1-KM1-CA-156687-01NCI NIH HHS KM1 CA156687NCI NIH HHS U01 CA093324NCI NIH HHS U01 CA093326NCI NIH HHS U01 CA093329NCI NIH HHS U01 CA093332NCI NIH HHS U01 CA093339NCI NIH HHS U01 CA093344NCI NIH HHS U01 CA093348
6 · The paper itself

Abstract

purposeThe impact of financial burden among patients with cancer has not yet been measured in a way that accounts for inter-relationships between quality of life, perceived quality of care, disease status, and sociodemographic characteristics. PATIENTS AND

methodsIn a national, prospective, observational, population- and health care systems-based cohort study, patients with colorectal or lung cancer were enrolled from 2003 to 2006 within 3 months of diagnosis. For this analysis, surviving patients who were either disease free or had advanced disease were resurveyed a median 7.3 years from diagnosis. Structural equation modeling was used to investigate relationships between financial burden, quality of life, perceived quality of care, and sociodemographic characteristics.

resultsAmong 1,000 participants enrolled from five geographic regions, five integrated health care systems, or 15 Veterans Administration Hospitals, 89% (n = 889) were cancer free, and 11% (n = 111) had advanced cancer. Overall, 48% (n = 482) reported difficulties living on their household income, and 41% (n = 396) believed their health care to be "excellent." High financial burden was associated with lower household income (adjusted odds ratio [OR] = 0.61 per $20k per year, P < .001) and younger age (adjusted OR = 0.63 per 10 years; P < .001). High financial burden was also associated with poorer quality of life (adjusted beta = -0.06 per burden category; P < .001). Better quality of life was associated with fewer perceptions of poorer quality of care (adjusted OR = 0.85 per 0.10 EuroQol units; P < .001).

conclusionFinancial burden is prevalent among cancer survivors and is related to patients' health-related quality of life. Future studies should consider interventions to improve patient education and engagement with regard to financial burden.

Indexed as

Cost of IllnessQuality of LifeAgedAged, 80 and overColorectal NeoplasmsFemaleHumansLung NeoplasmsMaleMiddle AgedPerceptionProspective StudiesQuality of Health CareSeverity of Illness IndexSurvivors

Identifiers

PMID25515717
PMCPMC4371118

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.