Evidence map›Paper›PMID 25515115›Full record

ArticleSleep2015

Effects of cognitive behavioral therapy for insomnia on suicidal ideation in veterans.

Mickey Trockel, Bradley E Karlin, C Barr Taylor, Gregory K Brown, Rachel Manber

3 registry-linked trialsOpen access · bronzeAbstract read
In one paragraph

Article in Sleep, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 82 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
82citing papers in PubMed, 2 pooled it
14.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04986007 naterminatednot on this mapstarted 2021, after this paper: background citation

Addressing Nocturnal Sleep/Wake Effects on Risk of Suicide in Older Adults (ANSWERS-OA): A Pilot, Open-Label, Randomized Controlled Trial of Digital Cognitive Behavioral Therapy for Insomnia

TypeinterventionalSponsorMICHAEL A GRANDNERRan2021 to 2025Enrolled23ConditionsSleep Initiation and Maintenance Disorders, Suicidal IdeationArmsDigital Cognitive Behavioral Therapy for Insomnia
NCT04988464 nacompletednot on this mapstarted 2021, after this paper: background citation

A Randomized Controlled Trial of Sleep Scholar: A Single-Session, Internet-Based Insomnia Intervention for College Students

TypeinterventionalSponsorAuburn UniversityRan2021 to 2021Enrolled64ConditionsInsomniaArmsSleep Scholar, Building Healthy Habits
NCT05390918 narecruitingnot on this mapstarted 2022, after this paper: background citation

Targeting Adolescent Insomnia to Lessen Overall Risk of Suicidal Behavior

TypeinterventionalSponsorJeff BridgeRan2022 to 2027Enrolled235ConditionsInsomnia, Suicidal Ideation, Suicide, AttemptedArmsTAILOR, Enhanced Usual Care
3 · Its place in the literature

Who cites it

82 citing papers in PubMed, 2 syntheses or guidelines pooled it, 185 citations in OpenAlex.

  1. Associations between insomnia and cardiovascular diseases: a meta-review and meta-analysis of observational and Mendelian randomization studies.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024
    Pooled it
  2. Pooled it
  3. Trial
  4. Trial
  5. Trial
  6. Trial
  7. Trial
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. [Insomniac symptoms and suicidality-link and management].Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2024
    Review

22 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 1 country.

Mickey TrockelSierra-Pacific Mental Illness Research, Education, and Clinical Center, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA.
Bradley E KarlinMental Health Services, U.S. Department of Veterans Affairs Central Office, Washington, DC.
C Barr TaylorStanford University School of Medicine, Palo Alto, CA.
Gregory K BrownMental Illness Research, Education, and Clinical Center, Philadelphia Veterans Affairs Medical Center, Philadelphia, PA.
Rachel ManberSierra-Pacific Mental Illness Research, Education, and Clinical Center, Veterans Affairs Palo Alto Health Care System, Palo Alto, CA.
VA Palo Alto Health Care System · USJohns Hopkins University · USPalo Alto University · USVeterans Health Administration · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the effects of cognitive behavioral therapy for insomnia (CBT-I) on suicidal ideation among Veterans with insomnia.

designLongitudinal data collected in the course of an uncontrolled evaluation of a large-scale CBT-I training program.

settingOutpatient and residential treatment facilities.

participantsFour hundred five Veterans presenting for treatment of insomnia.

interventionsCognitive behavioral therapy for insomnia (CBT-I). MEASUREMENT AND

resultsAt baseline, 32% of patients, compared with 21% at final assessment, endorsed some level of suicidal ideation [χ(2)(df = 1) = 125; P < 0.001]. After adjusting for demographic variables and baseline insomnia severity, each 7-point decrease in Insomnia Severity Index (ISI) score achieved during CBT-I treatment was associated with a 65% (OR = 0.35; 95% CI = 0.24 to 0.52) reduction in odds of suicidal ideation. The effect of change in insomnia severity on change in depression severity was also significant. After controlling for change in depression severity and other variables in the model, the effect of change in insomnia severity on change in suicidal ideation remained significant.

conclusionThis evaluation of the largest dissemination of CBT-I in the United States found a clinically meaningful reduction in suicidal ideation among Veterans receiving CBT-I. The mechanisms by which effective treatment of insomnia with CBT-I reduces suicide risk are unknown and warrant investigation. The current results may have significant public health implications for preventing suicide among Veterans.

Indexed as

Cognitive Behavioral TherapySuicidal IdeationSuicide PreventionAdultAgedAged, 80 and overDepressive DisorderFemaleHumansMaleMiddle AgedOutpatientsSleep Initiation and Maintenance DisordersSuicideTreatment OutcomeUnited Statescognitive behavioral therapydisseminationinsomnia, suicidal ideationVeterans

Identifiers

PMID25515115
PMCPMC4288607
OpenAlexW1967295279

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.