Evidence map›Paper›PMID 25514973›Full record

ArticleBMC pediatrics2014

Improved nutrient intake following implementation of the consensus standardised parenteral nutrition formulations in preterm neonates--a before-after intervention study.

Srinivas Bolisetty, Pramod Pharande, Lakshman Nirthanakumaran, Timothy Quy-Phong Do, David Osborn, John Smyth, John Sinn, Kei Lui

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC pediatrics, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Standard formulas and individualised parenteral nutrition preparations in very low birth weight infants.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2025
    Article
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Optimizing nutrition of the preterm infant.Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2017
    Article
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Srinivas BolisettyDivision of Newborn Services, Royal Hospital for Women, Sydney, Australia. Srinivas.bolisetty@sesiahs.health.nsw.gov.au.
Pramod PharandeDivision of Newborn Services, Royal Hospital for Women, Sydney, Australia. drpramodpharande@gmail.com.
Lakshman NirthanakumaranUniversity of New South Wales, Sydney, Australia. lakshman.nirthanakumaran@gmail.com.
Timothy Quy-Phong DoUniversity of New South Wales, Sydney, Australia. do.timothy@gmail.com.
David OsbornUniversity of Sydney and RPA Newborn Care, Royal Prince Alfred Hospital, Sydney, Australia. david.osborn@sydney.edu.au.
John SmythDivision of Newborn Services, Royal Hospital for Women, Sydney, Australia. john.smyth@sesiahs.health.nsw.gov.au.
John SinnDepartment of Neonatology, Royal North Shore Hospital, University of Sydney and, Sydney, Australia. John.sinn@health.nsw.gov.au.
Kei LuiDivision of Newborn Services, Royal Hospital for Women, Sydney, Australia. kei.lui@sesiahs.health.nsw.gov.au.
Royal Hospital for Women · AUUNSW Sydney · AURoyal North Shore Hospital · AURoyal Prince Alfred Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNew standardised parenteral nutrition (SPN) formulations were implemented in July 2011 in many neonatal intensive care units in New South Wales following consensus group recommendations. The aim was to evaluate the efficacy and safety profile of new consensus formulations in preterm infants born less than 32 weeks.

methodsA before-after intervention study conducted at a tertiary neonatal intensive care unit. Data from the post-consensus cohort (2011 to 2012) were prospectively collected and compared retrospectively with a pre-consensus cohort of neonates (2010).

resultsPost-consensus group commenced parenteral nutrition (PN) significantly earlier (6 v 11 hours of age, p 0.005). In comparison to the pre-consensus cohort, there was a higher protein intake from day 1 (1.34 v 0.49 g/kg, p 0.000) to day 7 (3.55 v 2.35 g/kg, p 0.000), higher caloric intake from day 1 (30 v 26 kcal/kg, p 0.004) to day 3 (64 v 62 kcal/kg, p 0.026), and less daily fluid intake from day 3 (105.8 v 113.8 mL/kg, p 0.011) to day 7 (148.8 v 156.2 mL/kg, p 0.025), and reduced duration of lipid therapy (253 v 475 hr, p 0.011). This group also had a significantly greater weight gain in the first 4 weeks (285 v 220 g, p 0.003).

conclusionsNew consensus SPN solutions provided better protein intake in the first 7 days and were associated with greater weight gain in the first 4 weeks. However, protein intake on day 1 was below the consensus goal of 2 g/kg/day.

Indexed as

Infant, PrematureParenteral NutritionWeight GainConsensus Statements as TopicDietary ProteinsEnergy IntakeGuideline AdherenceHumansIntensive Care Units, NeonatalNew South WalesProspective StudiesRetrospective StudiesDietary Proteins

Identifiers

PMID25514973
PMCPMC4275977
OpenAlexW2137686740

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.