Evidence map›Paper›PMID 25514096›Full record

ArticlePharmacogenetics and genomics2015

PharmGKB summary: very important pharmacogene information for CFTR.

Ellen M McDonagh, John P Clancy, Russ B Altman, Teri E Klein

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Pharmacogenetics and genomics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Ellen M McDonaghDepartments of aGenetics, Stanford School of Medicine bBioengineering, Stanford University, Stanford, California cDivision of Pulmonary Medicine, Cincinnati Children's Hospital Medical Center dDepartment of Pediatrics, University of Cincinnati, Cincinnati, Ohio, USA.
John P Clancy
Russ B Altman
Teri E Klein

Funding

POSTDOCTORAL TRAINING IN MEDICAL INFORMATION SCIENCEST15LM007033 · NLM · STANFORD UNIVERSITY · PI SYLVIA KATINA PLEVRITIS · 1985 to 2026
$25.5M
PharmGKB: pharmacogenomics knowledge for precision medicineR24GM061374 · NIGMS · STANFORD UNIVERSITY · PI ALTMAN, RUSS BIAGIO, KLEIN, TERI ELLEN · 2010 to 2018
$25.2M
NIGMS NIH HHS R24 GM061374NIGMS NIH HHS R24 GM61374NLM NIH HHS T15 LM007033
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AminophenolsClinical Trials as TopicCystic FibrosisCystic Fibrosis Transmembrane Conductance RegulatorDrug Therapy, CombinationHumansMolecular Targeted TherapyPolymorphism, Single NucleotideQuinolonesAminophenolsCFTR protein, humanCystic Fibrosis Transmembrane Conductance RegulatorivacaftorQuinolones

Identifiers

PMID25514096
PMCPMC4336773

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.