ReviewVirulence2014
Effector triggered immunity.
Review in Virulence, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed.
- Research Progress on Heavy Metals as Regulators of Bacterial Virulence in aPathogens (Basel, Switzerland) · 2026Review
- Integrated Transcriptomic and Metabolomic Analysis Reveals the Meat Production Features in Hybrid Sheep.Animals : an open access journal from MDPI · 2026Article
- Guards and decoys: RIPoptosome and inflammasome pathway regulators of bacterial effector-triggered immunity.PLoS pathogens · 2025Review
- Plant-Fungi Interactions: Where It Goes?Biology · 2023Review
- Molecular insights into the responses of barley to yellow mosaic disease through transcriptome analysis.BMC plant biology · 2023Article
- Insights to Gossypium defense response against Verticillium dahliae: the Cotton Cancer.Functional & integrative genomics · 2023Review
- Legumes Regulate Symbiosis with Rhizobia via Their Innate Immune System.International journal of molecular sciences · 2023Review
- Effector-Triggered Trained Immunity: An Innate Immune Memory to Microbial Virulence Factors?Toxins · 2022Article
- Antimicrobial peptide expression in the cockroach gut during enterobacterial infection is specific and influenced by type III secretion.Biology open · 2022Article
- Analysis of Bacteria-Triggered Inflammasome: Activation in Neutrophils by Immunoblot.Methods in molecular biology (Clifton, N.J.) · 2022Article
- Verticillium dahliae effector VDAL protects MYB6 from degradation by interacting with PUB25 and PUB26 E3 ligases to enhance Verticillium wilt resistance.The Plant cell · 2021Article
- Keeping in Touch with Type-III Secretion System Effectors: Mass Spectrometry-Based Proteomics to Study Effector-Host Protein-Protein Interactions.International journal of molecular sciences · 2020Review
- The pyrin inflammasome in host-microbe interactions.Current opinion in microbiology · 2020Review
- Mechanisms of Effector-Mediated Immunity Revealed by the Accidental Human PathogenFrontiers in cellular and infection microbiology · 2020Review
- The Role of a Glucosinolate-Derived Nitrile in Plant Immune Responses.Frontiers in plant science · 2020Article
- Effector-triggered immunity and pathogen sensing in metazoans.Nature microbiology · 2020Review
- Transcriptome profiling reveals the response process of tomato carrying Cf-19 and Cladosporium fulvum interaction.BMC plant biology · 2019Article
- The evolutionary history of LysM-RLKs (LYKs/LYRs) in wild tomatoes.BMC evolutionary biology · 2019Article
- NRG1 functions downstream of EDS1 to regulate TIR-NLR-mediated plant immunity inProceedings of the National Academy of Sciences of the United States of America · 2018Article
- Nucleolar fibrillarin is an evolutionarily conserved regulator of bacterial pathogen resistance.Nature communications · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Pathogenic bacteria produce virulence factors called effectors, which are important components of the infection process. Effectors aid in pathogenesis by facilitating bacterial attachment, pathogen entry into or exit from the host cell, immunoevasion, and immunosuppression. Effectors also have the ability to subvert host cellular processes, such as hijacking cytoskeletal machinery or blocking protein translation. However, host cells possess an evolutionarily conserved innate immune response that can sense the pathogen through the activity of its effectors and mount a robust immune response. This "effector triggered immunity" (ETI) was first discovered in plants but recent evidence suggest that the process is also well conserved in metazoans. We will discuss salient points of the mechanism of ETI in metazoans from recent studies done in mammalian cells and invertebrate model hosts.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.