Evidence map›Paper›PMID 25512705›Full record

ReviewGenetics & epigenetics2013

Unexplored potentials of epigenetic mechanisms of plants and animals-theoretical considerations.

Istvan Seffer, Zoltan Nemeth, Gyula Hoffmann, Robert Matics, A Gergely Seffer, Akos Koller

Abstract readReview
In one paragraph

Review in Genetics & epigenetics, 2013. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Macrophage-targeted delivery of siRNA to silenceBioengineering & translational medicine · 2022
    Article
  4. The epigenetic regulation of HIF-1α by SIRT1 in MPP(+) treated SH-SY5Y cells.Biochemical and biophysical research communications · 2016
    Article
  5. Article
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Istvan SefferSeffer-Renner Medical Clinic, Budapest, Hungary.
Zoltan NemethSeffer-Renner Medical Clinic, Budapest, Hungary. ; Department of Pathophysiology and Gerontology, Medical School, and Szentagothai Res Centre, University of Pecs, Pecs, Hungary.
Gyula HoffmannInstitute of Biology, Faculty of Sciences, University of Pecs, Pecs, Hungary.
Robert MaticsDepartment of Pathophysiology and Gerontology, Medical School, and Szentagothai Res Centre, University of Pecs, Pecs, Hungary.
A Gergely SefferSurgery Clinic, Medical School, University of Pecs, Pecs, Hungary.
Akos KollerDepartment of Pathophysiology and Gerontology, Medical School, and Szentagothai Res Centre, University of Pecs, Pecs, Hungary. ; Department of Physiology, New York Medical College, Valhalla NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Morphological and functional changes of cells are important for adapting to environmental changes and associated with continuous regulation of gene expressions. Genes are regulated-in part-by epigenetic mechanisms resulting in alternating patterns of gene expressions throughout life. Epigenetic changes responding to the environmental and intercellular signals can turn on/off specific genes, but do not modify the DNA sequence. Most epigenetic mechanisms are evolutionary conserved in eukaryotic organisms, and several homologs of epigenetic factors are present in plants and animals. Moreover, in vitro studies suggest that the plant cytoplasm is able to induce a nuclear reassembly of the animal cell, whereas others suggest that the ooplasm is able to induce condensation of plant chromatin. Here, we provide an overview of the main epigenetic mechanisms regulating gene expression and discuss fundamental epigenetic mechanisms and factors functioning in both plants and animals. Finally, we hypothesize that animal genome can be reprogrammed by epigenetic factors from the plant protoplast.

Indexed as

DNA methylationenvironmental signalsepigenetic mechanismsgene expressionhistone acetylationprotoplastreprogramming

Identifiers

PMID25512705
PMCPMC4222336

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.